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federal_register: 2014-25532

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document_number title type abstract publication_date pub_year pub_month html_url pdf_url agency_names agency_ids excerpts regulation_id_numbers
2014-25532 Draft Guidance for Industry on Qualification for the Use of Galactomannan in Serum and Bronchoalveolar Lavage Fluid; Availability Notice The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled "Draft Guidance on Qualification of Biomarker--Galactomannan in Studies of Treatments of Invasive Aspergillosis." This draft guidance provides recommendations on the use of Galactomannan detection in serum and/or bronchoalveolar lavage (BAL) fluid as the sole microbiological criterion to classify patients as having probable invasive Aspergillosis (IA) for enrollment in clinical trials. This draft guidance provides the context of use for which this biomarker drug development tool (DDT) is qualified through the Center for Drug Evaluation and Research (CDER) DDT Qualification Program. In the Federal Register of January 7, 2014, FDA announced the availability of a guidance for industry entitled "Qualification Process for Drug Development Tools," which described the process that would be used to qualify DDTs and to make new DDT qualification recommendations available on FDA's Web site. The qualification recommendations in this draft guidance were developed using the process described in that guidance. 2014-10-27 2014 10 https://www.federalregister.gov/documents/2014/10/27/2014-25532/draft-guidance-for-industry-on-qualification-for-the-use-of-galactomannan-in-serum-and https://www.govinfo.gov/content/pkg/FR-2014-10-27/pdf/2014-25532.pdf Health and Human Services Department; Food and Drug Administration 221,199 The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled "Draft Guidance on Qualification of Biomarker--Galactomannan in Studies of Treatments of Invasive Aspergillosis." This draft guidance...  

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