id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id FDA-2017-N-0763-1452,FDA,FDA-2017-N-0763,Letter from Antonio McGee to FDA DDM,Other,Letter(s),2019-02-22T05:00:00Z,2019,2,2019-02-22T05:00:00Z,,2019-02-22T15:15:44Z,,0,0,0900006483a98e8d FDA-2017-N-0763-0867,FDA,FDA-2017-N-0763,Food Labeling: Health Claims; Soy Protein and Coronary Heart Disease; Extension of Comment Period,Proposed Rule,Extension of Comment Period,2018-01-17T05:00:00Z,2018,1,2018-01-17T05:00:00Z,2018-03-20T03:59:59Z,2023-08-08T01:02:42Z,2018-00683,0,0,0900006482e18b55 FDA-2017-N-0763-0568,FDA,FDA-2017-N-0763,Request for Extension from Soyfoods Association of North America,Other,Request for Extension,2018-01-02T05:00:00Z,2018,1,2018-01-02T05:00:00Z,,2018-01-02T14:51:45Z,,0,0,0900006482d7f5ea FDA-2017-N-0763-0067,FDA,FDA-2017-N-0763,"Reference_64 van Raaij_1982_Influence of diets containing containing casein, soy isolate, and soy concentrate",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:37Z,,0,0,0900006482c14082 FDA-2017-N-0763-0074,FDA,FDA-2017-N-0763,Reference_77 Kurowska_1997_Effects of substituting dietary soybean protein and oil for milk protein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:39:24Z,,0,0,0900006482c142aa FDA-2017-N-0763-0099,FDA,FDA-2017-N-0763,Reference_92 Wu_2005_A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:28Z,,0,0,0900006482c143b2 FDA-2017-N-0763-0098,FDA,FDA-2017-N-0763,Reference_93 Steele_The effect on serum cholesterol levels of substituting milk with a soya beverage,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:27Z,,0,0,0900006482c143b3 FDA-2017-N-0763-0110,FDA,FDA-2017-N-0763,Reference_101 Swain_2002_Iron indexes and total antioxidant status in responses to soy protein intake in perimenopausal,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:31Z,,0,0,0900006482c143f3 FDA-2017-N-0763-0125,FDA,FDA-2017-N-0763,Reference_126 D'Amico_1992_Effect of vegetarian soy diet on hyperlipidaemia in nephrotic syndrome,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:27Z,,0,0,0900006482c14455 FDA-2017-N-0763-0160,FDA,FDA-2017-N-0763,Reference_151 Jenkins_2003_Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:00:38Z,,0,0,0900006482c144bb FDA-2017-N-0763-0156,FDA,FDA-2017-N-0763,"Reference_155 Jones_2005_Effects of a diet high in plant sterols, vegetable proteins, and viscous fibers",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:00:37Z,,0,0,0900006482c144bf FDA-2017-N-0763-0121,FDA,FDA-2017-N-0763,"Reference_110 Nilausen_1998_Variable lipemic response to dietary soy protein in healthy,normolipemic men",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:50:24Z,,0,0,0900006482c145ea FDA-2017-N-0763-0120,FDA,FDA-2017-N-0763,Reference_111 Nilausen_1999_Lipoprotein(a) and dietary proteins-casein lowers lipoprotein(a) concentrations,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:50:24Z,,0,0,0900006482c145eb FDA-2017-N-0763-0145,FDA,FDA-2017-N-0763,"Reference_146 Zittermann-2004_Short-term effects of high soy. supplementation on sex hormones, bone markers",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:20Z,,0,0,0900006482c146ae FDA-2017-N-0763-0153,FDA,FDA-2017-N-0763,Reference_158_NHLBI_2003_Seventh Report of the Joint National Committee on Prevention,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:00:36Z,,0,0,0900006482c146b3 FDA-2017-N-0763-0229,FDA,FDA-2017-N-0763,Reference_222 Yang_2005_Longitudinal study of soy food intake and blood pressure among middle-aged and elderly Chinese,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:10:50Z,,0,0,0900006482c146db FDA-2017-N-0763-0223,FDA,FDA-2017-N-0763,Reference_228 The ATBC cancer prevention study group._1994_The effect of vitamin E and beta carotene on the incidence,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:10:48Z,,0,0,0900006482c146e1 FDA-2017-N-0763-0037,FDA,FDA-2017-N-0763,Reference_34 Wong_1995_Cholesterol synthesis and absorption by 2h2o and 18o-cholesterol,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:16:45Z,,0,0,0900006482c13ffb FDA-2017-N-0763-0196,FDA,FDA-2017-N-0763,Reference_195 Gardner_2001_The effect of soy protein with or without isoflavones relative to milk protein onplasma lipids,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:06:07Z,,0,0,0900006482c1493f FDA-2017-N-0763-0194,FDA,FDA-2017-N-0763,Reference_197 Chen_2006_Effect of soya protein on serum lipid profile and lipoprotein concentrations in patients,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:06:06Z,,0,0,0900006482c14941 FDA-2017-N-0763-0203,FDA,FDA-2017-N-0763,Reference_208 Jenkins_2000_Effect of soy-based breakfast cereal on blood lipids and oxidized low-density lipoprotein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:07:44Z,,0,0,0900006482c14973 FDA-2017-N-0763-0216,FDA,FDA-2017-N-0763,Reference_215 Ho_2000_Intake of soy products is associated with better plasma lipid profiles,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:09:53Z,,0,0,0900006482c149be FDA-2017-N-0763-0018,FDA,FDA-2017-N-0763,"Reference_13 USDA_2016_Soy Milk,USDA National Nutrient Database for Standard Reference, 28",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:14:28Z,,0,0,0900006482c13fbf FDA-2017-N-0763-0015,FDA,FDA-2017-N-0763,"Reference_16 IOM_DRIs for Water, Potassium, Sodium, Chloride, and Sulfate",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:14:28Z,,0,0,0900006482c13fc2 FDA-2017-N-0763-0060,FDA,FDA-2017-N-0763,Reference_51 Potter_1976_Greater bile acid excretion with soy bean than with cow milk in infants,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:22:34Z,,0,0,0900006482c1423d FDA-2017-N-0763-0090,FDA,FDA-2017-N-0763,Reference_81 Gaddi_1987_Hypercholesterolaemia treated by soybean protein diet,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:43:46Z,,0,0,0900006482c142ae FDA-2017-N-0763-0109,FDA,FDA-2017-N-0763,Reference_102 Sirtori_Soy milk with a high glycitein content does not reduce low-density lipoprotein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:31Z,,0,0,0900006482c143f4 FDA-2017-N-0763-0127,FDA,FDA-2017-N-0763,Reference_124_Mercer_1987_Effects of human plasma lipids of substituting soybean protein isolate for milk protein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:27Z,,0,0,0900006482c14453 FDA-2017-N-0763-0137,FDA,FDA-2017-N-0763,Reference_134 Ham _1993_Endocrinological response to soy protein and fiber in mildly hypercholesterolemic men,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:08Z,,0,0,0900006482c14476 FDA-2017-N-0763-0136,FDA,FDA-2017-N-0763,"Reference_135 Roughead_2005_Controlled substitution of soy protein for meat protein-effects on calcium retention, bone",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:08Z,,0,0,0900006482c14477 FDA-2017-N-0763-0162,FDA,FDA-2017-N-0763,Reference_169 Jayagopal_2002_Beneficial effects of soy phytoestrogen intake in postmenopausal women,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:02:06Z,,0,0,0900006482c144eb FDA-2017-N-0763-0151,FDA,FDA-2017-N-0763,Reference_140 Liao_2007_Effectiveness of a soy-based compared with a traditional low-calorie diet on weight loss,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:21Z,,0,0,0900006482c146a6 FDA-2017-N-0763-0146,FDA,FDA-2017-N-0763,"Reference_145_Vigna_2000_Plasma lipoproteins in soy-treated postmenopausal women-a double-blind, placebo-controlled trial",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:20Z,,0,0,0900006482c146ab FDA-2017-N-0763-0166,FDA,FDA-2017-N-0763,Reference_165 McVeigh_2006_Effect of soy protein varying in isoflavone content on serum lipids,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:02:07Z,,0,0,0900006482c146ba FDA-2017-N-0763-0173,FDA,FDA-2017-N-0763,Reference_178 Takatsuka_2000_Hypocholesterolemic effect of soymilk supplementation with usual diet in premenopausal,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:03:25Z,,0,0,0900006482c14919 FDA-2017-N-0763-0011,FDA,FDA-2017-N-0763,Reference Index,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:11:40Z,,0,0,0900006482c13ba7 FDA-2017-N-0763-0005,FDA,FDA-2017-N-0763,Reference_06 NRC_2011_Reference Manual on Scientific Evidence Third Edition,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:11:39Z,,0,0,0900006482c13f9a FDA-2017-N-0763-0002,FDA,FDA-2017-N-0763,010 Reference_09 AHRQ_2002_Systems to Rate the Scientific Evidence - 2002,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:11:37Z,,0,0,0900006482c13f9d FDA-2017-N-0763-0012,FDA,FDA-2017-N-0763,Reference_19 Tormala_2006_Serum cholesterol efflux potential in postmenopausal women treated with isolated isoflavones,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:14:27Z,,0,0,0900006482c13fc5 FDA-2017-N-0763-0050,FDA,FDA-2017-N-0763,Reference_41 Sirtori_1979_Clinical experience with the soybean protein diet in the treatment of hypercholesterolemia,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:19:11Z,,0,0,0900006482c1401d FDA-2017-N-0763-0045,FDA,FDA-2017-N-0763,Reference_46 Lovati_1987_Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:19:10Z,,0,0,0900006482c14022 FDA-2017-N-0763-0195,FDA,FDA-2017-N-0763,Reference_196 Hori_2001_Soy protein hydrolyzate with bound phospholipids reduces serum cholesterol levels,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:06:06Z,,0,0,0900006482c14940 FDA-2017-N-0763-0192,FDA,FDA-2017-N-0763,Reference_199_West_2005_Effects of including soy protein in a blood cholesterol-lowering diet on markers,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:06:06Z,,0,0,0900006482c1496a FDA-2017-N-0763-0219,FDA,FDA-2017-N-0763,"Reference_212 He_2005_Effect of soybean protein on blood pressure-a randomized, controlled trial",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:09:54Z,,0,0,0900006482c149bb FDA-2017-N-0763-0054,FDA,FDA-2017-N-0763,Reference_57_Vessby_1982_The effects on lipid and carbohydrate metabolism of replacing some animal protein by soy-protein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:22:32Z,,0,0,0900006482c1407b FDA-2017-N-0763-0070,FDA,FDA-2017-N-0763,Reference_61 Bonanome_1988_Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:37Z,,0,0,0900006482c1407f FDA-2017-N-0763-0069,FDA,FDA-2017-N-0763,Reference_62 Tabibi_2010_Effects of soy consumption on serum lipids and apoproteins in peritoneal dialysis patients,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:37Z,,0,0,0900006482c14080 FDA-2017-N-0763-0027,FDA,FDA-2017-N-0763,Reference_24 Vega-Lopez_2005-Plasma antioxidant capacity in response to diets high in soy,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:15:41Z,,0,0,0900006482c14213 FDA-2017-N-0763-0062,FDA,FDA-2017-N-0763,Reference_69 Stephenson_2005_Effect of soy protein-rich diet on renal function in young adults,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:35Z,,0,0,0900006482c14287 FDA-2017-N-0763-0100,FDA,FDA-2017-N-0763,Reference_91 Anderson_2005_Weight loss and lipid changes with low-energy diets-comparator study,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:28Z,,0,0,0900006482c143b1 FDA-2017-N-0763-0097,FDA,FDA-2017-N-0763,Reference_94 Deibert_2004_Weight loss without losing muscle mass in pre-obese and obese subjects,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:27Z,,0,0,0900006482c143b4 FDA-2017-N-0763-0177,FDA,FDA-2017-N-0763,Reference_174 Mangano-2013-Soy proteins and isoflavones reduce interleukin-6 but not serum lipids in older women,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:03:26Z,,0,0,0900006482c144f0 FDA-2017-N-0763-0132,FDA,FDA-2017-N-0763,Reference_139 D'Amico_1991_Effect of dietary proteins and lipids in patients with membranous nephropathy,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:07Z,,0,0,0900006482c146a5 FDA-2017-N-0763-0150,FDA,FDA-2017-N-0763,Reference_141 Li_2005_Long-term efficacy of soy-based meal replacements vs and individualized diet plan in obese type,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:21Z,,0,0,0900006482c146a7 FDA-2017-N-0763-0149,FDA,FDA-2017-N-0763,Reference_142 Chiechi_2002_The effects of a soy rich diet on serum lipids-the menfis randomized trial,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:20Z,,0,0,0900006482c146a8 FDA-2017-N-0763-0191,FDA,FDA-2017-N-0763,Reference_180 Murkies_Dietary flour supplmentation decreases post-menopausal hot flushes,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:04:32Z,,0,0,0900006482c1491b FDA-2017-N-0763-0183,FDA,FDA-2017-N-0763,Reference_188 Hoie_2006_Ultra heat treatment destroys cholesterol-lowering effect of soy protein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:04:30Z,,0,0,0900006482c1492f FDA-2017-N-0763-0206,FDA,FDA-2017-N-0763,Reference_205 Desroches_2004_Soy protein favorably affects LDL size independently of isoflavones in hypercholesterolemic,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:07:44Z,,0,0,0900006482c14970 FDA-2017-N-0763-0204,FDA,FDA-2017-N-0763,Reference_207 Gardner_2007_Effect of two types of soy milk and dairy milk on plasma lipids in hypercholesterolemic,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:07:44Z,,0,0,0900006482c14972 FDA-2017-N-0763-0021,FDA,FDA-2017-N-0763,"Reference_10 IOM DRIs for Dietary Fats, Chapter 8",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:14:28Z,,0,0,0900006482c13f9e FDA-2017-N-0763-0013,FDA,FDA-2017-N-0763,Reference_18 Siefker_2006_Safety and antioxidant effects of a modest soy protein intervention in hemodialysis patients,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:14:27Z,,0,0,0900006482c13fc4 FDA-2017-N-0763-0080,FDA,FDA-2017-N-0763,Reference_71 Thorp_2008_Soy food consumption does not lower LDL cholesterol in either equol or nonequol producers,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:39:25Z,,0,0,0900006482c14289 FDA-2017-N-0763-0072,FDA,FDA-2017-N-0763,Reference_79 Ashton_Effects of soy as tofu vs meat on lipoprotein concentrations,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:39:23Z,,0,0,0900006482c142ac FDA-2017-N-0763-0089,FDA,FDA-2017-N-0763,"Reference_82 Duane_Effects of soybean protein and very low dietary cholesterol on serum lipids, biliary lipids",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:43:46Z,,0,0,0900006482c142af FDA-2017-N-0763-0087,FDA,FDA-2017-N-0763,Reference_84 Hermansen_2005_Effects of soy supplementation on blood lipids and arterial function in hypercholesterolaemic,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:43:46Z,,0,0,0900006482c142b1 FDA-2017-N-0763-0108,FDA,FDA-2017-N-0763,Reference_103 Sirtori_1985_Cholesterol-lowering and HDL-raising properties of lecithinated soy proteins in type II,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:31Z,,0,0,0900006482c143f5 FDA-2017-N-0763-0123,FDA,FDA-2017-N-0763,Reference_128 Soroka_ 1998_Comparison of a vegetable-based (soya) and an animal-based low-protein diet,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:26Z,,0,0,0900006482c14457 FDA-2017-N-0763-0140,FDA,FDA-2017-N-0763,Reference_131 Jenkins_2002_A dietary portfolio approach to cholesterol reduction-combined effects of plant sterols,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:09Z,,0,0,0900006482c14473 FDA-2017-N-0763-0144,FDA,FDA-2017-N-0763,Reference_147 Cicero_2002_Effects of a new soy_beta-sitosterol supplement on plasma lipids in moderately,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:19Z,,0,0,0900006482c144b7 FDA-2017-N-0763-0164,FDA,FDA-2017-N-0763,Reference_167 Teixeira_2004_Isolated soy protein consumption reduces urinary albumin excretion and improves the serum,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:02:07Z,,0,0,0900006482c144e9 FDA-2017-N-0763-0175,FDA,FDA-2017-N-0763,Reference_176 Bakhit_1994_Intake of 25 g of soybean protein with or without soybean fiber alters plasma lipids,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:03:25Z,,0,0,0900006482c144f2 FDA-2017-N-0763-0105,FDA,FDA-2017-N-0763,Reference_106 Carroll_1978_Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:30Z,,0,0,0900006482c145e6 FDA-2017-N-0763-0103,FDA,FDA-2017-N-0763,Reference_108 Sacks_1983_Lack of an effect of dairy protein (casein) and soy protein on plasma cholesterol,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:30Z,,0,0,0900006482c145e8 FDA-2017-N-0763-0148,FDA,FDA-2017-N-0763,Reference_143 Chiechi_2002_Efficacy of a soy rich diet in preventing postmenopausal osteoporosis,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:59:20Z,,0,0,0900006482c146a9 FDA-2017-N-0763-0009,FDA,FDA-2017-N-0763,Reference_02 Balk_2005_ Effects of soy on health Outcomes,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:11:40Z,,0,0,0900006482c13f96 FDA-2017-N-0763-0187,FDA,FDA-2017-N-0763,Reference_184 Greany_2004_Probiotic consumption does not enhance the cholesterol-lowering effect of soy in postmenopausal,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:04:31Z,,0,0,0900006482c1491f FDA-2017-N-0763-0208,FDA,FDA-2017-N-0763,Reference_203 Lichtenstein_2002_Lipoprotein response to diets high in soy or animal protein with and without isoflavones,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:07:45Z,,0,0,0900006482c1496e FDA-2017-N-0763-0217,FDA,FDA-2017-N-0763,215 Reference_214 Chan_2007_Isoflavone intake in persons at high risk of cardiovascular events-implications for vascular,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:09:53Z,,0,0,0900006482c149bd FDA-2017-N-0763-0046,FDA,FDA-2017-N-0763,Reference_45 Gardner-Thorpe_2003_Dietary supplements of soya flour lowers serum testosterone concentrations,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:19:10Z,,0,0,0900006482c14021 FDA-2017-N-0763-0022,FDA,FDA-2017-N-0763,Reference_29 Gallagher_2004_The effect of soy protein isolate on bone metabolism,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:15:39Z,,0,0,0900006482c13ff6 FDA-2017-N-0763-0038,FDA,FDA-2017-N-0763,Reference_33 Merz-Demlow_2000_Soy isoflavones improve plasma lipids in normocholesterolemic,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:16:45Z,,0,0,0900006482c13ffa FDA-2017-N-0763-0055,FDA,FDA-2017-N-0763,Reference_56 Fumagalli_1982_Fecal cholesterol excretion studies in type II hypercholesterolemic patients,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:22:32Z,,0,0,0900006482c1407a FDA-2017-N-0763-0061,FDA,FDA-2017-N-0763,Reference_50 Borodin_2009_Effects of two-month consumption of 30 g a day of soy protein isolate or skimmed curd protein,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:22:34Z,,0,0,0900006482c14239 FDA-2017-N-0763-0076,FDA,FDA-2017-N-0763,Reference_75 Ridges_2001_Cholesterol lowering benefits of soy and linseed enriched foods,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:39:24Z,,0,0,0900006482c142a8 FDA-2017-N-0763-0096,FDA,FDA-2017-N-0763,"Reference_95 Puska_2002_Soy in hypercholesterolaemia_ a double-blind, placebo-controlled trial",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:27Z,,0,0,0900006482c143ed FDA-2017-N-0763-0094,FDA,FDA-2017-N-0763,Reference_97 Allison_2003_A novel soy-based meal replacement formula for weight loss among obese individuals,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:46:26Z,,0,0,0900006482c143ef FDA-2017-N-0763-0107,FDA,FDA-2017-N-0763,Reference_104 Sirtori_1999_Double-blind study of the addition of high-protein soya milk v. cows' milk to the diet,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:48:31Z,,0,0,0900006482c143f6 FDA-2017-N-0763-0122,FDA,FDA-2017-N-0763,Reference_129 Shige_199_-Effects of soy protein isolate (SPI) and casein on the postprandial lipemia,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:26Z,,0,0,0900006482c14458 FDA-2017-N-0763-0139,FDA,FDA-2017-N-0763,Reference_132 Jenkins_2000_The effect on serum lipids and oxidized low-density lipoprotein of supplementing,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:09Z,,0,0,0900006482c14474 FDA-2017-N-0763-0163,FDA,FDA-2017-N-0763,Reference_168 Murray_2003_Soy protein isolate with isoflavones does not prevent estradiol-induced endometrial hyperplasia,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:02:06Z,,0,0,0900006482c144ea FDA-2017-N-0763-0167,FDA,FDA-2017-N-0763,Reference_164 Kohno_2006_Decreases in serum triacylglycerol and visceral fat mediated by dietary soybean,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:02:07Z,,0,0,0900006482c146b9 FDA-2017-N-0763-0231,FDA,FDA-2017-N-0763,Reference_220 Rosell_2004_Soy intake and blood cholesterol concentrations-a cross-sectional study,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:10:50Z,,0,0,0900006482c146d9 FDA-2017-N-0763-0227,FDA,FDA-2017-N-0763,Reference_224 Zhang_2003_Soy food consumption is associated with lower risk of coronary heart disease in Chinese,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T17:10:49Z,,0,0,0900006482c146dd FDA-2017-N-0763-0068,FDA,FDA-2017-N-0763,Reference_63 St-Onge_2007_Supplementation with soy-protein-rich foods does not enhance weight loss,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:37Z,,0,0,0900006482c14081 FDA-2017-N-0763-0058,FDA,FDA-2017-N-0763,Reference_53 Campbell_2006_Effects of soy or milk protein during a high-fat feeding challenge on oxidative stress,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:22:33Z,,0,0,0900006482c1423f FDA-2017-N-0763-0064,FDA,FDA-2017-N-0763,Reference_67 Pipe_2009_Soy protein reduces serum LDL cholesterol,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:33:36Z,,0,0,0900006482c14285 FDA-2017-N-0763-0130,FDA,FDA-2017-N-0763,Reference_121 Huff_1984_Turnover of very low-density lipoprotein-apoprotein b is increased by substitution,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:28Z,,0,0,0900006482c14450 FDA-2017-N-0763-0126,FDA,FDA-2017-N-0763,Reference_125_D'Amico_1992_Effect of dietary manipulation on the lipid abnormalities and urinary protein loss,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:55:27Z,,0,0,0900006482c14454 FDA-2017-N-0763-0138,FDA,FDA-2017-N-0763,Reference_133 Jenkins_2000_Effect of soy protein foods on low-denisty lipoprotein oxidation and ex vivo,Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:09Z,,0,0,0900006482c14475 FDA-2017-N-0763-0135,FDA,FDA-2017-N-0763,"Reference_136 Yamashita_1998_Arterial compliance, blood pressure, plasma leptin, and plasma lipids in women",Supporting & Related Material,Background Material,2017-10-31T04:00:00Z,2017,10,,,2017-10-31T16:58:08Z,,0,0,0900006482c14478