id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id FDA-2015-F-4317-0129,FDA,FDA-2015-F-4317,Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants; Confirmation of Effective Date,Rule,Final Rule,2020-01-31T05:00:00Z,2020,1,2020-01-31T05:00:00Z,,2020-01-31T14:50:26Z,2020-01060,0,0,09000064843166d0 FDA-2015-F-4317-0062,FDA,FDA-2015-F-4317,Reference 3 Barlow 2006 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:32Z,,0,0,09000064837ab434 FDA-2015-F-4317-0065,FDA,FDA-2015-F-4317,Reference 6 FAP 5A4810_C_memo2 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:58Z,,0,0,09000064837ab437 FDA-2015-F-4317-0070,FDA,FDA-2015-F-4317,Reference 11 Ethyl Acrylate Carcinogenicity Review Memorandum Final 06_21_2018 (2) - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:33Z,,0,0,09000064837ab497 FDA-2015-F-4317-0073,FDA,FDA-2015-F-4317,Reference 14 2018 06 21 Myrcene Carcinogenic Final Tox Memo ATKhan - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:58Z,,0,0,09000064837ab49a FDA-2015-F-4317-0058,FDA,FDA-2015-F-4317,Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Rule,Final Rule,2018-10-09T04:00:00Z,2018,10,2018-10-09T04:00:00Z,2018-11-09T04:59:59Z,2018-11-09T02:03:58Z,2018-21807,0,0,09000064837a9dd2 FDA-2015-F-4317-0066,FDA,FDA-2015-F-4317,Reference 8 FEMA Response Package 041116_Redacted - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:07Z,,0,0,09000064837ab494 FDA-2015-F-4317-0071,FDA,FDA-2015-F-4317,Reference 12 NTP Report on Carcinogens Background Document for Ethyl Acrylate Dockets - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:41Z,,0,0,09000064837ab498 FDA-2015-F-4317-0060,FDA,FDA-2015-F-4317,Reference 1 Bevans 2017 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:07Z,,0,0,09000064837ab432 FDA-2015-F-4317-0063,FDA,FDA-2015-F-4317,Reference 4 FEMA letter_04302018_Redacted - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:40Z,,0,0,09000064837ab435 FDA-2015-F-4317-0072,FDA,FDA-2015-F-4317,Reference 13 2018-06-21-Methyleugenol Carcinogenic Evaluation Tox memoFINAL - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:49Z,,0,0,09000064837ab499 FDA-2015-F-4317-0074,FDA,FDA-2015-F-4317,Reference 15 FAP 5A4810 Pulegone Final Toxicology Memo NA FINAL - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:22:07Z,,0,0,09000064837ab49b FDA-2015-F-4317-0069,FDA,FDA-2015-F-4317,Reference 10 Boobis 2006 IPCS MOA - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:24Z,,0,0,09000064837ab496 FDA-2015-F-4317-0059,FDA,FDA-2015-F-4317,REFERENCE LIST for FAP 5A4810 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:19:53Z,,0,0,09000064837ab431 FDA-2015-F-4317-0061,FDA,FDA-2015-F-4317,Reference 2 JECFA 2006-Annex 4 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:23Z,,0,0,09000064837ab433 FDA-2015-F-4317-0064,FDA,FDA-2015-F-4317,Reference 5 FAP 5A4810_C_memo1_2016-06-24 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:20:49Z,,0,0,09000064837ab436 FDA-2015-F-4317-0068,FDA,FDA-2015-F-4317,Reference 9 Benzophenone Flavors Review of the carcinogencity of benzophenone final 06_21_2018 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:21:16Z,,0,0,09000064837ab495 FDA-2015-F-4317-0075,FDA,FDA-2015-F-4317,Reference 16 MODE OF ACTION OF PULEGONE ON THE URINARY BLADDER OF F344 RATS (DA ROC - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:22:17Z,,0,0,09000064837ab49c FDA-2015-F-4317-0076,FDA,FDA-2015-F-4317,Reference 17 Pyridine Final Toxicology Memo.TTyler.06.27.18 - re: Food Additive Regulations; Synthetic Flavoring Agents and Adjuvants,Supporting & Related Material,Background Material,2018-10-09T04:00:00Z,2018,10,,,2018-10-09T15:22:25Z,,0,0,09000064837ab49d FDA-2015-F-4317-0057,FDA,FDA-2015-F-4317,Comment from Flavor and Extract Manufacturers Association (FEMA),Other,Supplemental Comment,2018-10-04T04:00:00Z,2018,10,2018-10-04T04:00:00Z,,2018-10-04T22:04:36Z,,0,0,090000648379aa02 FDA-2015-F-4317-0039,FDA,FDA-2015-F-4317,"Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition; Extension of Comment Period",Proposed Rule,Extension of Comment Period,2016-02-23T05:00:00Z,2016,2,2016-02-23T05:00:00Z,2016-05-04T03:59:59Z,2016-05-03T22:00:20Z,2016-03708,0,0,0900006481e80505 FDA-2015-F-4317-0036,FDA,FDA-2015-F-4317,Request to Extend Comment Period from Flavor and Extract Manufacturers Association (FEMA),Other,Request for Extension,2016-02-02T05:00:00Z,2016,2,2016-02-02T05:00:00Z,,2016-02-02T14:27:57Z,,0,0,0900006481e4079f FDA-2015-F-4317-0008,FDA,FDA-2015-F-4317,Request for Extension from The Flavor and Extract Manufacturers Association of the United States (FEMA),Other,Request for Extension,2016-01-13T05:00:00Z,2016,1,2016-01-13T05:00:00Z,,2016-01-13T17:21:37Z,,0,0,0900006481e0511a FDA-2015-F-4317-0005,FDA,FDA-2015-F-4317,"Reference 3 Letter adding co-petitioner for FAP 5A4810 re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:17:16Z,,0,0,0900006481de8524 FDA-2015-F-4317-0007,FDA,FDA-2015-F-4317,"Reference 5 References cited in FAP 5A4810 re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:17:27Z,,0,0,0900006481de8526 FDA-2015-F-4317-0003,FDA,FDA-2015-F-4317,"Reference 1 Redacted FAP 5A4810 re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:17:04Z,,0,0,0900006481de7014 FDA-2015-F-4317-0004,FDA,FDA-2015-F-4317,"Reference 2 Nonredacted FAP 5A4810 (contains copyrighted materials) re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:17:11Z,,0,0,0900006481de8523 FDA-2015-F-4317-0006,FDA,FDA-2015-F-4317,"Reference 4 Environmental document FAP 5A4810 re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:17:22Z,,0,0,0900006481de8525 FDA-2015-F-4317-0002,FDA,FDA-2015-F-4317,"LIST OF REFERENCES re Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Supporting & Related Material,Background Material,2016-01-05T05:00:00Z,2016,1,,,2016-01-05T13:16:48Z,,0,0,0900006481de7013 FDA-2015-F-4317-0001,FDA,FDA-2015-F-4317,"Center for Science in the Public Interest, Natural Resources Defense Council, Center for Food Safety, Consumers Union, Improving Kids’ Environment, Center for Environmental Health, Environmental Working Group, Environmental Defense Fund, and James Huff; Filing of Food Additive Petition",Proposed Rule,Notice of Proposed Rulemaking (NPRM),2016-01-04T05:00:00Z,2016,1,2016-01-04T05:00:00Z,2016-03-05T04:59:59Z,2016-03-04T17:00:48Z,2015-33011,0,0,0900006481de405d