id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id
EPA-HQ-OPPT-2024-0403-0097,EPA,EPA-HQ-OPPT-2024-0403,"N-(1,3-Dimethylbutyl)-N′-phenyl-pphenylenediamine (6PPD) and its transformation product, 6PPDquinone; Regulatory Investigation under the Toxic Substances Control Act (TSCA); Extension of the Comment Period",Proposed Rule,Advance Notice of Proposed Rulemaking (ANPRM),2025-01-17T05:00:00Z,2025,1,2025-01-17T05:00:00Z,,2025-01-21T13:41:57Z,2025-00731,0,0,09000064868d0ecc
EPA-HQ-OPPT-2024-0403-0066,EPA,EPA-HQ-OPPT-2024-0403,"Laws and Regulations: Listing Motor Vehicle Tires Containing N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) as a Priority Product",Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:44:11Z,,0,0,09000064867dc400
EPA-HQ-OPPT-2024-0403-0080,EPA,EPA-HQ-OPPT-2024-0403,E‑Waste Recycling Emits Large Quantities of Emerging Aromatic Amines and Organophosphites: A Poorly Recognized Source for Another Two Classes of Synthetic Antioxidants,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:39:05Z,,0,0,09000064867e4ccf
EPA-HQ-OPPT-2024-0403-0089,EPA,EPA-HQ-OPPT-2024-0403,Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Causes Abnormal Locomotion Behaviors and Neurodegeneration in Caenorhabditis elegans,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:44:49Z,,0,0,09000064867eaa6b
EPA-HQ-OPPT-2024-0403-0018,EPA,EPA-HQ-OPPT-2024-0403,Toxicity of Rubber Chemicals Towards Three-day Chicken Embryos,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:43:20Z,,0,0,09000064867dc3d0
EPA-HQ-OPPT-2024-0403-0060,EPA,EPA-HQ-OPPT-2024-0403,"Tire Wear Particles in the Aquatic Environment - A Review on Generation, Analysis, Occurrence, Fate and Effects",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:43:08Z,,0,0,09000064867dc3fa
EPA-HQ-OPPT-2024-0403-0074,EPA,EPA-HQ-OPPT-2024-0403,The Tire-Derived Chemical 6PPD-quinone Is Lethally Toxic to the White-Spotted Char Salvelinus leucomaenis pluvius but Not to Two Other Salmonid Species,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:41:38Z,,0,0,09000064867dc408
EPA-HQ-OPPT-2024-0403-0077,EPA,EPA-HQ-OPPT-2024-0403,Polyethylene Nanoparticles at Environmentally Relevant Concentrations Enhances Neurotoxicity and Accumulation of 6-PPD Quinone in Caenorhabditis elegans,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:42:16Z,,0,0,09000064867dc40b
EPA-HQ-OPPT-2024-0403-0083,EPA,EPA-HQ-OPPT-2024-0403,"Transformation Product Formation upon Heterogeneous Ozonation of the Tire Rubber Antioxidant 6PPD (N‑(1,3-dimethylbutyl)‑N′‑phenyl‑p‑phenylenediamine)",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:58:09Z,,0,0,09000064867e4cd2
EPA-HQ-OPPT-2024-0403-0003,EPA,EPA-HQ-OPPT-2024-0403,6PPD-Quinone: Revised Toxicity Assessment and Quantification with a Commercial Standard,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:57:56Z,,0,0,09000064867dc3ad
EPA-HQ-OPPT-2024-0403-0037,EPA,EPA-HQ-OPPT-2024-0403,EPA's EPI Suite - Estimation Program Interface,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:55:45Z,,0,0,09000064867dc3e3
EPA-HQ-OPPT-2024-0403-0056,EPA,EPA-HQ-OPPT-2024-0403,Where the Rubber Meets the Road: Emerging Environmental Impacts of Tire Wear Particles and their Chemical Cocktails,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:47:35Z,,0,0,09000064867dc3f6
EPA-HQ-OPPT-2024-0403-0075,EPA,EPA-HQ-OPPT-2024-0403,Widespread Occurrence of Two Typical N-substituted p-phenylenediamines and Their Quinones in Humans: Association with Oxidative Stress and Liver Damage,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:54:40Z,,0,0,09000064867dc409
EPA-HQ-OPPT-2024-0403-0045,EPA,EPA-HQ-OPPT-2024-0403,Oslo and Paris Convention (OSPAR) Commission Hazardous Substances Series (dimethylbutylamino)diphenylamine (6PPD),Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:57:15Z,,0,0,09000064867dc3eb
EPA-HQ-OPPT-2024-0403-0057,EPA,EPA-HQ-OPPT-2024-0403,"Urban Roadway Runoff Is Lethal to Juvenile Coho, Steelhead, and Chinook Salmonids, But Not Congeneric Sockeye",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:49:30Z,,0,0,09000064867dc3f7
EPA-HQ-OPPT-2024-0403-0079,EPA,EPA-HQ-OPPT-2024-0403,Acute Toxicity of 6PPD Quinone to Early Life Stage Juvenile Chinook  (Oncorhynchus tshawytscha) and Coho (Oncorhynchus kisutch) Salmon,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:55:06Z,,0,0,09000064867dc40d
EPA-HQ-OPPT-2024-0403-0002,EPA,EPA-HQ-OPPT-2024-0403,"Acute Toxicity of the Tire Rubber-Derived Chemical 6PPD-quinone to Four Fishes of Commercial, Cultural, and Ecological Importance",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:46:06Z,,0,0,09000064867dc3ac
EPA-HQ-OPPT-2024-0403-0005,EPA,EPA-HQ-OPPT-2024-0403,Acute Cerebrovascular Effects in Juvenile Coho Salmon Exposed to Roadway Runoff,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:45:53Z,,0,0,09000064867dc3c3
EPA-HQ-OPPT-2024-0403-0023,EPA,EPA-HQ-OPPT-2024-0403,Environmental Fate of Tire-rubber Related Pollutants 6PPD and 6PPD-Q: A Review,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:51:26Z,,0,0,09000064867dc3d5
EPA-HQ-OPPT-2024-0403-0061,EPA,EPA-HQ-OPPT-2024-0403,"Widespread Occurrence and Transport of p‑Phenylenediamines and Their Quinones in Sediments across Urban Rivers, Estuaries, Coasts, and Deep-Sea Regions",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:50:09Z,,0,0,09000064867dc3fb
EPA-HQ-OPPT-2024-0403-0006,EPA,EPA-HQ-OPPT-2024-0403,Earthjustice Citizen Petition to EPA under TSCA Section 21 to Prohibit 6PPD in Tires,Supporting & Related Material,Letter,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:57:42Z,,0,0,09000064867dc3c4
EPA-HQ-OPPT-2024-0403-0047,EPA,EPA-HQ-OPPT-2024-0403,"Occurrence of Polymer Additives 1,3-Diphenylguanidine (DPG), N‑(1,3 Dimethylbutyl)‑N′‑phenyl-1,4-benzenediamine (6PPD), and Chlorinated Byproducts in Drinking Water: Contribution from Plumbing Polymer Materials",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:57:29Z,,0,0,09000064867dc3ed
EPA-HQ-OPPT-2024-0403-0058,EPA,EPA-HQ-OPPT-2024-0403,Four-week Repeated Exposure to Tire-derived 6PPD Quinone Causes Multiple Organ Injury in Male BALB/c Mice,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:49:43Z,,0,0,09000064867dc3f8
EPA-HQ-OPPT-2024-0403-0063,EPA,EPA-HQ-OPPT-2024-0403,State of Washington Department of Ecology's 6PPD Alternatives Assessment Hazard Criteria,Supporting & Related Material,Publication - Other Governmental,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:50:34Z,,0,0,09000064867dc3fd
EPA-HQ-OPPT-2024-0403-0044,EPA,EPA-HQ-OPPT-2024-0403,Letter from Petitioners on the Advance Notice of Proposed Rulemaking for TSCA Section 6(a) Risk Management in August 2024,Supporting & Related Material,Letter,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:57:02Z,,0,0,09000064867dc3ea
EPA-HQ-OPPT-2024-0403-0085,EPA,EPA-HQ-OPPT-2024-0403,Biotransformation of 6PPD-quinone In Vitro Using RTL-W1 Cell Line,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:39:31Z,,0,0,09000064867e4cd4
EPA-HQ-OPPT-2024-0403-0025,EPA,EPA-HQ-OPPT-2024-0403,Using High-Resolution Mass Spectrometry to Identify Organic Contaminants Linked to Urban Stormwater Mortality Syndrome in Coho Salmon,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:42:29Z,,0,0,09000064867dc3d7
EPA-HQ-OPPT-2024-0403-0010,EPA,EPA-HQ-OPPT-2024-0403,Q & A: USTMA's Stage 1 Alternatives Analysis For 6PPD in Tires,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:41:00Z,,0,0,09000064867dc3c8
EPA-HQ-OPPT-2024-0403-0012,EPA,EPA-HQ-OPPT-2024-0403,Effect of Ozone on Rubbers: Countermeasures and Unsolved Problems,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:42:03Z,,0,0,09000064867dc3ca
EPA-HQ-OPPT-2024-0403-0049,EPA,EPA-HQ-OPPT-2024-0403,Toxicological Effects of 6PPD and 6PPD Quinone in Zebrafish Larvae,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:42:55Z,,0,0,09000064867dc3ef
EPA-HQ-OPPT-2024-0403-0087,EPA,EPA-HQ-OPPT-2024-0403,p-Phenylenediamine Antioxidants in PM2.5: The Underestimated Urban Air Pollutants,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:45:02Z,,0,0,09000064867e9e27
EPA-HQ-OPPT-2024-0403-0039,EPA,EPA-HQ-OPPT-2024-0403,Exposure to 6PPD Quinone at Environmentally Relevant Concentrations Inhibits Both Lifespan and Healthspan in C. elegans,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:40:22Z,,0,0,09000064867dc3e5
EPA-HQ-OPPT-2024-0403-0014,EPA,EPA-HQ-OPPT-2024-0403,Flexsys Strengthens its Decarbonization Goals by Committing to Science-Based Target,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:48:38Z,,0,0,09000064867dc3cc
EPA-HQ-OPPT-2024-0403-0028,EPA,EPA-HQ-OPPT-2024-0403,"Microplastics: Occurrence, Effects, and Sources of Releases to the Environment in Denmark",Supporting & Related Material,Report,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:52:18Z,,0,0,09000064867dc3da
EPA-HQ-OPPT-2024-0403-0032,EPA,EPA-HQ-OPPT-2024-0403,Establishing an In Vitro Model to Assess the Toxicity of 6PPD-Quinone and Other Tire Wear Transformation Products,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:52:56Z,,0,0,09000064867dc3de
EPA-HQ-OPPT-2024-0403-0038,EPA,EPA-HQ-OPPT-2024-0403,Hazardous Organic Chemicals in Rubber Recycled Tire Playgrounds and Pavers,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:55:58Z,,0,0,09000064867dc3e4
EPA-HQ-OPPT-2024-0403-0048,EPA,EPA-HQ-OPPT-2024-0403,Responses of Soil and Collembolan (Folsomia candida) Gut Microbiomes to 6PPD-Q Pollution,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:43:58Z,,0,0,09000064867dc3ee
EPA-HQ-OPPT-2024-0403-0009,EPA,EPA-HQ-OPPT-2024-0403,Environmental Exposure of Road Borders to Zinc,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:48:13Z,,0,0,09000064867dc3c7
EPA-HQ-OPPT-2024-0403-0017,EPA,EPA-HQ-OPPT-2024-0403,"Association between 6PPD-quinone Exposure and BMI, Influenza, and Diarrhea in Children",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:49:04Z,,0,0,09000064867dc3cf
EPA-HQ-OPPT-2024-0403-0054,EPA,EPA-HQ-OPPT-2024-0403,Screening Information Dataset (SIDs) Initial Assessment Report on 6PPD,Supporting & Related Material,Report,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:47:09Z,,0,0,09000064867dc3f4
EPA-HQ-OPPT-2024-0403-0065,EPA,EPA-HQ-OPPT-2024-0403,Synthesis and Toxicity Evaluation of Tire Rubber-Derived Quinones,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:51:01Z,,0,0,09000064867dc3ff
EPA-HQ-OPPT-2024-0403-0024,EPA,EPA-HQ-OPPT-2024-0403,Saving Coho Salmon: Alternatives for 6PPD,Supporting & Related Material,Report,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:51:39Z,,0,0,09000064867dc3d6
EPA-HQ-OPPT-2024-0403-0015,EPA,EPA-HQ-OPPT-2024-0403,"Concentration and Leachability of N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its Quinone Transformation Product (6PPD-Q) in Road Dust Collected in Tokyo, Japan",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:48:52Z,,0,0,09000064867dc3cd
EPA-HQ-OPPT-2024-0403-0019,EPA,EPA-HQ-OPPT-2024-0403,Western Reserve Chemicals: WESTCO Product Profile - 6PPD,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:49:17Z,,0,0,09000064867dc3d1
EPA-HQ-OPPT-2024-0403-0026,EPA,EPA-HQ-OPPT-2024-0403,"Environmental Profiles, Hazard Identification and Toxicological Hallmarks of Emerging Tire Rubber-related Contaminants 6PPD and 6PPD-quinone",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:51:52Z,,0,0,09000064867dc3d8
EPA-HQ-OPPT-2024-0403-0033,EPA,EPA-HQ-OPPT-2024-0403,Occurrence of P-phenylenediamine Antioxidants (PPDs) and PPDs-derived Quinones in Indoor Dust,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:53:09Z,,0,0,09000064867dc3df
EPA-HQ-OPPT-2024-0403-0030,EPA,EPA-HQ-OPPT-2024-0403,European Chemicals Agency (ECHA) - 6PPD Registration Dossier,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:41:13Z,,0,0,09000064867dc3dc
EPA-HQ-OPPT-2024-0403-0088,EPA,EPA-HQ-OPPT-2024-0403,Ecotoxicology A Ubiquitous Tire Rubber-Derived Chemical Induces Acute Mortality in Coho Salmon,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:44:37Z,,0,0,09000064867eaa66
EPA-HQ-OPPT-2024-0403-0052,EPA,EPA-HQ-OPPT-2024-0403,Exposure to 6-PPD Quinone Enhances Lipid Accumulation through Activating Metabolic Sensors of SBP-1 and MDT-15 in Caenorhabditis elegans,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:43:33Z,,0,0,09000064867dc3f2
EPA-HQ-OPPT-2024-0403-0081,EPA,EPA-HQ-OPPT-2024-0403,"Widespread N‑(1,3-Dimethylbutyl)‑N′‑phenyl‑p‑phenylenediamine Quinone in Size-Fractioned Atmospheric Particles and Dust of Different Indoor Environments",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:40:09Z,,0,0,09000064867e4cd0
EPA-HQ-OPPT-2024-0403-0067,EPA,EPA-HQ-OPPT-2024-0403,Treading Water: Tire Wear Particle Leachate Recreates an Urban Runoff Mortality Syndrome in Coho but Not Chum Salmon,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:53:35Z,,0,0,09000064867dc401
EPA-HQ-OPPT-2024-0403-0034,EPA,EPA-HQ-OPPT-2024-0403,Investigation of 6PPD-Quinone in Rubberized Asphalt Concrete Mixtures,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:40:47Z,,0,0,09000064867dc3e0
EPA-HQ-OPPT-2024-0403-0046,EPA,EPA-HQ-OPPT-2024-0403,Uses of Scrap Rubber Tires,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:42:42Z,,0,0,09000064867dc3ec
EPA-HQ-OPPT-2024-0403-0084,EPA,EPA-HQ-OPPT-2024-0403,Addressing Durability of Rubber Compounds,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:39:43Z,,0,0,09000064867e4cd3
EPA-HQ-OPPT-2024-0403-0007,EPA,EPA-HQ-OPPT-2024-0403,EPA ECOTOX Knowledgebase - 6PPD and 6PPD-quinone Chemical Knowledgebase Dashboard,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:47:48Z,,0,0,09000064867dc3c5
EPA-HQ-OPPT-2024-0403-0050,EPA,EPA-HQ-OPPT-2024-0403,Workshop on Motor Vehicle Tires Containing 6PPD - Priority Product Proposal - July 2021 - YouTube,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:46:31Z,,0,0,09000064867dc3f0
EPA-HQ-OPPT-2024-0403-0068,EPA,EPA-HQ-OPPT-2024-0403,"New Evidence of Rubber-Derived Quinones in Water, Air, and Soil",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:41:25Z,,0,0,09000064867dc402
EPA-HQ-OPPT-2024-0403-0016,EPA,EPA-HQ-OPPT-2024-0403,Occurrence of P-phenylenediamine Antioxidants in Human Urine,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:39:57Z,,0,0,09000064867dc3ce
EPA-HQ-OPPT-2024-0403-0086,EPA,EPA-HQ-OPPT-2024-0403,EPA Small Business Innovation Research (SBIR) Program Webpage,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:40:34Z,,0,0,09000064867e4dd2
EPA-HQ-OPPT-2024-0403-0073,EPA,EPA-HQ-OPPT-2024-0403,Variation in the Toxicity of Sediment-associated Substituted Phenylamine Antioxidants to an Epibenthic (Hyalella azteca)  and Endobenthic (Tubifex tubifex) Invertebrate,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:54:27Z,,0,0,09000064867dc407
EPA-HQ-OPPT-2024-0403-0051,EPA,EPA-HQ-OPPT-2024-0403,Uptake and Biotransformation of the Tire Rubber-derived Contaminants 6PPD and 6PPD Quinone in the Zebrafish Embryo (Danio rerio),Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:46:44Z,,0,0,09000064867dc3f1
EPA-HQ-OPPT-2024-0403-0059,EPA,EPA-HQ-OPPT-2024-0403,"EPA Decision Letter to the TSCA Section 21 Petition Regarding N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (CASRN 793-24-8) (6PPD) in Tires",Supporting & Related Material,Letter,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:49:56Z,,0,0,09000064867dc3f9
EPA-HQ-OPPT-2024-0403-0064,EPA,EPA-HQ-OPPT-2024-0403,"Results of Aquatic Toxicity Tests of Chemicals Conducted by Ministry of the Environment in Japan since March, 2019",Supporting & Related Material,Data,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:50:48Z,,0,0,09000064867dc3fe
EPA-HQ-OPPT-2024-0403-0070,EPA,EPA-HQ-OPPT-2024-0403,"Listing Motor Vehicle Tires Containing N-(1,3-Dimethylbutyl)-N′-phenyl-pphenylenediamine (6PPD) as a Priority Product",Supporting & Related Material,Report,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:54:01Z,,0,0,09000064867dc404
EPA-HQ-OPPT-2024-0403-0004,EPA,EPA-HQ-OPPT-2024-0403,"6PPD in Tires: A concern for Playgrounds, Artificial Turf, and More",Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:46:19Z,,0,0,09000064867dc3c2
EPA-HQ-OPPT-2024-0403-0008,EPA,EPA-HQ-OPPT-2024-0403,Recurrent Die-Offs of Adult Coho Salmon Returning to Spawn in Puget Sound Lowland Urban Streams,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:48:01Z,,0,0,09000064867dc3c6
EPA-HQ-OPPT-2024-0403-0071,EPA,EPA-HQ-OPPT-2024-0403,Chiral Perspective Evaluations: Enantioselective Hydrolysis of 6PPD and 6PPD-quinone in Water and Enantioselective Toxicity to Gobiocypris rarus and Oncorhynchus mykiss,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:53:22Z,,0,0,09000064867dc405
EPA-HQ-OPPT-2024-0403-0091,EPA,EPA-HQ-OPPT-2024-0403,"EPA Meeting with The National Tribal Toxics Council (NTTC) on  July 22, 2024",Supporting & Related Material,Meeting Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:45:27Z,,0,0,09000064867f49c5
EPA-HQ-OPPT-2024-0403-0036,EPA,EPA-HQ-OPPT-2024-0403,PubChem Compound Summary Webpage on 6PPD,Supporting & Related Material,Report,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:55:32Z,,0,0,09000064867dc3e2
EPA-HQ-OPPT-2024-0403-0069,EPA,EPA-HQ-OPPT-2024-0403,State of Washington Department of Ecology's Safer Products for Washington Webpage,Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:53:49Z,,0,0,09000064867dc403
EPA-HQ-OPPT-2024-0403-0029,EPA,EPA-HQ-OPPT-2024-0403,"Acute Toxicity of a Tire Rubber-Derived Chemical, 6PPD Quinone, to Freshwater Fish and Crustacean Species",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:52:31Z,,0,0,09000064867dc3db
EPA-HQ-OPPT-2024-0403-0021,EPA,EPA-HQ-OPPT-2024-0403,Exposure to the Tire Rubber-Derived Contaminant 6PPD-Quinone Causes Mitochondrial Dysfunction In Vivo,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:51:13Z,,0,0,09000064867dc3d3
EPA-HQ-OPPT-2024-0403-0042,EPA,EPA-HQ-OPPT-2024-0403,More Than a First Flush: Urban Creek Storm Hydrographs Demonstrate Broad Contaminant Pollutographs,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:56:36Z,,0,0,09000064867dc3e8
EPA-HQ-OPPT-2024-0403-0062,EPA,EPA-HQ-OPPT-2024-0403,Interstate Regulatory Technology Council (IRTC) - What We Know on 6PPD and 6PPD-quinone,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:50:21Z,,0,0,09000064867dc3fc
EPA-HQ-OPPT-2024-0403-0020,EPA,EPA-HQ-OPPT-2024-0403,U.S. Tire Manufacturers Association and U.S. Geological Survey Partner for Joint Research Into 6PPD Alternatives Press Release,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:44:24Z,,0,0,09000064867dc3d2
EPA-HQ-OPPT-2024-0403-0082,EPA,EPA-HQ-OPPT-2024-0403,Occurrence of Substituted p‑Phenylenediamine Antioxidants in Dusts,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:39:18Z,,0,0,09000064867e4cd1
EPA-HQ-OPPT-2024-0403-0027,EPA,EPA-HQ-OPPT-2024-0403,"Uptake, Metabolism, and Accumulation of Tire Wear Particle-Derived Compounds in Lettuce",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:52:05Z,,0,0,09000064867dc3d9
EPA-HQ-OPPT-2024-0403-0031,EPA,EPA-HQ-OPPT-2024-0403,"First Report on the Occurrence of N‑(1,3 Dimethylbutyl)‑N′‑phenyl‑p‑phenylenediamine (6PPD) and 6PPD-Quinone as Pervasive Pollutants in Human Urine from South China",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:52:44Z,,0,0,09000064867dc3dd
EPA-HQ-OPPT-2024-0403-0040,EPA,EPA-HQ-OPPT-2024-0403,EPA's 2024 Acute Aquatic Life Screening Value for 6PPD-quinone in Freshwater,Supporting & Related Material,Publication - USEPA,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:56:10Z,,0,0,09000064867dc3e6
EPA-HQ-OPPT-2024-0403-0043,EPA,EPA-HQ-OPPT-2024-0403,EPA's 2024 Acute Aquatic Life Screening Value for 6PPD in Freshwater,Supporting & Related Material,Publication - USEPA,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:56:49Z,,0,0,09000064867dc3e9
EPA-HQ-OPPT-2024-0403-0055,EPA,EPA-HQ-OPPT-2024-0403,Transformation Products of Tire Rubber Antioxidant 6PPD in Heterogeneous Gas-Phase Ozonation: Identification and Environmental Occurrence,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:47:22Z,,0,0,09000064867dc3f5
EPA-HQ-OPPT-2024-0403-0011,EPA,EPA-HQ-OPPT-2024-0403,Acute and Sub-chronic Toxicity of 6PPD-quinone to Early-life Stage Lake Trout (Salvelinus namaycush),Supporting & Related Material,,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:48:26Z,,0,0,09000064867dc3c9
EPA-HQ-OPPT-2024-0403-0041,EPA,EPA-HQ-OPPT-2024-0403,"Joined Fortune Chemical's Webpage on 6PPD Rubber Antioxidant: Characteristics, Applications, Combinations, and Considerations for Commercial Procurement",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:56:23Z,,0,0,09000064867dc3e7
EPA-HQ-OPPT-2024-0403-0053,EPA,EPA-HQ-OPPT-2024-0403,"Tyre and Road Wear Particles (TRWP) - A Review of Generation, Properties, Emissions, Human Health Risk, Ecotoxicity, and Fate in the Environment",Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:46:56Z,,0,0,09000064867dc3f3
EPA-HQ-OPPT-2024-0403-0072,EPA,EPA-HQ-OPPT-2024-0403,Abiotic Oxidative Transformation of 6PPD and 6PPD Quinone from Tires and Occurrence of their Products in Snow from Urban Roads and in Municipal Wastewater,Supporting & Related Material,Publication,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:54:14Z,,0,0,09000064867dc406
EPA-HQ-OPPT-2024-0403-0013,EPA,EPA-HQ-OPPT-2024-0403,Environmental Processes: Alternations of Pollutants,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:45:40Z,,0,0,09000064867dc3cb
EPA-HQ-OPPT-2024-0403-0035,EPA,EPA-HQ-OPPT-2024-0403,Letter from Monsanto Co. to EPA Regarding Toxicity Studies with Santoflex 44 Antioxidant in August 1992,Supporting & Related Material,Letter,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:55:19Z,,0,0,09000064867dc3e1
EPA-HQ-OPPT-2024-0403-0076,EPA,EPA-HQ-OPPT-2024-0403,6PPD-quinone Exposure Induces Neuronal Mitochondrial Dysfunction to Exacerbate Lewy Neurites Formation Induced by α-synuclein Preformed Fibrils Seeding,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:54:52Z,,0,0,09000064867dc40a
EPA-HQ-OPPT-2024-0403-0022,EPA,EPA-HQ-OPPT-2024-0403,"Analysis, Environmental Occurrence, Fate and Potential Toxicity of Tire Wear Compounds 6PPD and 6PPD-quinone",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:43:46Z,,0,0,09000064867dc3d4
EPA-HQ-OPPT-2024-0403-0090,EPA,EPA-HQ-OPPT-2024-0403,"Mechanisms of Ozonation of N-(1,3-Dimethylbutyl)-N′-Phenyl-p-Phenylenediamine",Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:45:15Z,,0,0,09000064867eaad2
EPA-HQ-OPPT-2024-0403-0078,EPA,EPA-HQ-OPPT-2024-0403,Screening p-Phenylenediamine Antioxidants Their Transformation Products and Industrial Chemical Additives in Crumb Rubber and Elastomeric Consumer Products,Supporting & Related Material,Publication - Copyrighted Materials,2024-11-19T05:00:00Z,2024,11,,,2024-11-20T01:41:51Z,,0,0,09000064867dc40c
EPA-HQ-OPPT-2024-0403-0001,EPA,EPA-HQ-OPPT-2024-0403,"N-(1,3-Dimethylbutyl)-N′-phenyl-pphenylenediamine (6PPD) and its Transformation Product, 6PPDquinone; Regulatory Investigation Under the Toxic Substances Control Act (TSCA)",Proposed Rule,Advance Notice of Proposed Rulemaking (ANPRM),2024-11-19T05:00:00Z,2024,11,2024-11-19T05:00:00Z,2025-03-25T03:59:59Z,2025-03-26T01:00:38Z,2024-26894,0,0,09000064868277c9