id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id EPA-HQ-OPPT-2002-0056-0130,EPA,EPA-HQ-OPPT-2002-0056,TCE Acute Neurotox Route-to-Route final report,Supporting & Related Material,Report,2012-08-03T04:00:00Z,2012,8,,,2012-08-03T13:40:30Z,,0,0,09000064810be86d EPA-HQ-OPPT-2002-0056-0129,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics, USEPA, from Peter E. Voytek, Manager, HAP Task Force",Supporting & Related Material,"Letter, Memorandum, Email",2007-01-16T05:00:00Z,2007,1,,,2007-01-16T21:25:26Z,,0,0,09000064801f4305 EPA-HQ-OPPT-2002-0056-0128,EPA,EPA-HQ-OPPT-2002-0056,"Route to Route Extrapolation of 1,1,2-Trichloroethane Studies from the Oral Route to Inhalation Using Physiologically Based Pharmacokinetic Models: Reproductive Toxicity - Final",Supporting & Related Material,Report,2006-11-15T05:00:00Z,2006,11,,,2006-11-15T13:04:11Z,,0,0,09000064801df0e4 EPA-HQ-OPPT-2002-0056-0127,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane: Multigeneration Reproduction Study in Rats - Volume 1",Supporting & Related Material,Report,2006-08-03T04:00:00Z,2006,8,,,2006-10-23T16:41:10Z,,0,0,09000064801a75fd EPA-HQ-OPPT-2002-0056-0126,EPA,EPA-HQ-OPPT-2002-0056,"Letter to OPPT Document Control Office, USEPA, from Peter E. Voytek, Manager, HAP Task force, re: Testing Consent Order for 1,1,2- Trichloroethane Interim Report",Supporting & Related Material,"Letter, Memorandum, Email",2006-06-22T04:00:00Z,2006,6,,,2006-10-23T16:41:10Z,,0,0,090000648018c210 EPA-HQ-OPPT-2002-0056-0124,EPA,EPA-HQ-OPPT-2002-0056,"Letter to OPPT Document Control Office, USEPA, from Peter E. Voytek, Manager, HAP Task Force, re: Testing Consent Order for 1,1,2 Trichloroethane; Interim Report",Supporting & Related Material,"Letter, Memorandum, Email",2006-01-20T05:00:00Z,2006,1,,,2006-10-23T16:41:10Z,,0,0,09000064801165f2 EPA-HQ-OPPT-2002-0056-0123,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics, Room 6428, USEPA, from Peter E. Voytek, Ph. D., Manager, Task Force",Supporting & Related Material,"Letter, Memorandum, Email",2006-01-20T05:00:00Z,2006,1,,,2006-10-23T16:41:10Z,,0,0,0900006480103846 EPA-HQ-OPPT-2002-0056-0122,EPA,EPA-HQ-OPPT-2002-0056,"Route-to-Route Extrapolation of 1,1,2-Trichloroethane Studies from the Oral Route to Inhalation Using Physiologically Based Pharmacokinetic Models: Developmental Toxicity",Supporting & Related Material,Report,2005-10-20T04:00:00Z,2005,10,,,2006-10-23T16:41:10Z,,0,0,09000064800b62cc EPA-HQ-OPPT-2002-0056-0121,EPA,EPA-HQ-OPPT-2002-0056,"Route-to-Route Extrapolation of 1,1,2-Trichloroethane Studies from the Oral Route to Inhalation Using Physiologically Based Pharmacokinetic Models: Subchronic Neurotoxicity",Supporting & Related Material,Report,2005-10-20T04:00:00Z,2005,10,,,2006-10-23T16:41:10Z,,0,0,09000064800b62b7 EPA-HQ-OPPT-2002-0056-0120,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics, USEPA, from Peter E. Voytek, Manager, HAP Task Force, re: Testing Consent Order for 1,1,2 Trichloroethane; Interim Report",Supporting & Related Material,"Letter, Memorandum, Email",2005-08-16T14:48:17Z,2005,8,,,2006-10-23T16:41:10Z,,0,0,09000064800b62a1 EPA-HQ-OPPT-2002-0056-0117,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane: Subchronic Neurotoxicity Study in F344/DUCRL Rats (part 2 of 4)",Supporting & Related Material,Study,2005-08-16T04:00:00Z,2005,8,,,2006-10-23T16:41:10Z,,0,0,09000064800b624c EPA-HQ-OPPT-2002-0056-0118,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane: Subchronic Neurotoxicity Study in F344/DUCRL Rats (part 3 of 4)",Supporting & Related Material,Study,2005-08-16T04:00:00Z,2005,8,,,2006-10-23T16:41:10Z,,0,0,09000064800b626d EPA-HQ-OPPT-2002-0056-0116,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane: Subchronic Neurotoxicity Study in F344/DUCRL Rats (part 1 of 4)",Supporting & Related Material,Study,2005-08-16T04:00:00Z,2005,8,,,2006-10-23T16:41:10Z,,0,0,09000064800b6233 EPA-HQ-OPPT-2002-0056-0119,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane: Subchronic Neurotoxicity Study in F344/DUCRL Rats (part 4 of 4)",Supporting & Related Material,Study,2005-08-16T04:00:00Z,2005,8,,,2006-10-23T16:41:10Z,,0,0,09000064800b6283 EPA-HQ-OPPT-2002-0056-0115,EPA,EPA-HQ-OPPT-2002-0056,"A Prenatal Develomental Toxicity Study of 1,1,2-Trichloroethane Via Drinking Water In Rats",Supporting & Related Material,Report,2005-05-09T14:42:00Z,2005,5,,,2006-10-23T16:41:10Z,,0,0,09000064800b620b EPA-HQ-OPPT-2002-0056-0114,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Confidential Business Information Center (CBIC), from John Schaeffer, CITB/CCD, re: Addendum Modification to Enforceable Consent Agreement (ECA) for 1,1,2- Trichloroethane; CAS Register Number 79-00-5",Supporting & Related Material,"Letter, Memorandum, Email",2005-02-10T05:00:00Z,2005,2,,,2006-10-23T16:41:10Z,,0,0,09000064800b61f3 EPA-HQ-OPPT-2002-0056-0113,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Peter Voytek, HAP Task Force Manager, from Jim Willis, Director, USEPA, re: request for modifications",Supporting & Related Material,"Letter, Memorandum, Email",2005-01-24T05:00:00Z,2005,1,,,2006-10-23T16:41:10Z,,0,0,09000064800b61d8 EPA-HQ-OPPT-2002-0056-0112,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics, from Peter E. Voytek, Manager, HAP Task Force, re: Testing Consent Order for 1,1,2 Trichloroethane; Interim Report",Supporting & Related Material,"Letter, Memorandum, Email",2005-01-12T05:00:00Z,2005,1,,,2006-10-23T16:41:10Z,,0,0,09000064800b61bc EPA-HQ-OPPT-2002-0056-0111,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Peter E. Voytek, Ph.D, regarding Testing Consent Order for 1,1,2-Trichlorooethane; Request for Modification of Enforceable Consent Agreement.",Supporting & Related Material,"Letter, Memorandum, Email",2004-12-14T05:00:00Z,2004,12,,,2006-10-23T16:41:10Z,,0,0,09000064800b61a4 EPA-HQ-OPPT-2002-0056-0110,EPA,EPA-HQ-OPPT-2002-0056,"Prenatal Developmental Toxicity Testing of 1,1,2-Trichloroethane",Supporting & Related Material,Study,2004-11-09T05:00:00Z,2004,11,,,2006-10-23T16:41:10Z,,0,0,09000064800b6187 EPA-HQ-OPPT-2002-0056-0109,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Confidential Business Information Center (CBIC), from John Schaeffer, USEPA, re: Addendum Modification to Enforceable Consent Agreement (ECA) for 1,1,2-Trichloroethane (TCE) CAS No. 79-00-5",Supporting & Related Material,"Letter, Memorandum, Email",2004-11-02T05:00:00Z,2004,11,,,2006-10-23T16:41:10Z,,0,0,09000064800b6168 EPA-HQ-OPPT-2002-0056-0108,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL III (9 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b6155 EPA-HQ-OPPT-2002-0056-0100,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL I (1 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:09Z,,0,0,09000064800b6083 EPA-HQ-OPPT-2002-0056-0103,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2,-Trichloroethane in Rats. VOL II (4 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b60de EPA-HQ-OPPT-2002-0056-0104,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL II (5 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b60fe EPA-HQ-OPPT-2002-0056-0105,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL II (6 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b6112 EPA-HQ-OPPT-2002-0056-0106,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL III (7 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b6126 EPA-HQ-OPPT-2002-0056-0107,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL III (8 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b613d EPA-HQ-OPPT-2002-0056-0102,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL I (3 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:10Z,,0,0,09000064800b60c3 EPA-HQ-OPPT-2002-0056-0101,EPA,EPA-HQ-OPPT-2002-0056,"An Acute Neurotoxicity Study of 1,1,2-Trichloroethane in Rats. VOL I (2 of 9)",Supporting & Related Material,Report,2004-09-24T04:00:00Z,2004,9,,,2006-10-23T16:41:09Z,,0,0,09000064800b60a3 EPA-HQ-OPPT-2002-0056-0098,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Wardner G. Penberthy, DIrector, Chemical Control Division, USEPA to Dr. Peter Voytek, HAP Task Force Manager, re: Request for Modification (Docket No. OPPT-2002-0056) DCN 40040000154",Supporting & Related Material,"Letter, Memorandum, Email",2004-08-02T04:00:00Z,2004,8,,,2006-10-23T16:41:09Z,,0,0,09000064800b6051 EPA-HQ-OPPT-2002-0056-0096,EPA,EPA-HQ-OPPT-2002-0056,"Subchronic Neurotoxicity Testing of 1,1,2-Trichloroethane",Supporting & Related Material,Report,2004-07-27T04:00:00Z,2004,7,,,2006-10-23T16:41:09Z,,0,0,09000064800b6013 EPA-HQ-OPPT-2002-0056-0097,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics, from Peter E. Voytek, Manager, HAP Task Force, re: Testing Consent Order for 1,1,2 Trichloroethane",Supporting & Related Material,"Letter, Memorandum, Email",2004-07-27T04:00:00Z,2004,7,,,2006-10-23T16:41:09Z,,0,0,09000064800b6035 EPA-HQ-OPPT-2002-0056-0094,EPA,EPA-HQ-OPPT-2002-0056,"Testing Consent Order for 1,1,2-Trichloroethane; Study Plan for Acute Neurotoxicity Study",Supporting & Related Material,Report,2004-07-27T04:00:00Z,2004,7,,,2006-10-23T16:41:09Z,,0,0,09000064800b5fd9 EPA-HQ-OPPT-2002-0056-0095,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office, Office of Pollution Prevention and Toxics from Peter Voytek, Manager, HAP Task Force, re: Testing Consent Order for 1,1,2 Trichloroethane; Interim Report (Docket No. OPPT-2002-0056)",Supporting & Related Material,"Letter, Memorandum, Email",2004-07-02T04:00:00Z,2004,7,,,2006-10-23T16:41:09Z,,0,0,09000064800b5ff7 EPA-HQ-OPPT-2002-0056-0092,EPA,EPA-HQ-OPPT-2002-0056,"Route-to-Route Extrapolation of 1,1,2-Trichloroethane Studies from the Oral Route to Inhalation Using Physiologically Based Pharmacokinetic Models: Immunotoxicity",Supporting & Related Material,Report,2004-04-20T04:00:00Z,2004,4,,,2006-10-23T16:41:09Z,,0,0,09000064800b5fb0 EPA-HQ-OPPT-2002-0056-0091,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Peter Voytek, HAP Task Force Manager, from Wardner G. Penberthy, Acting Director, Chemical Control Division, USEPA, regarding 1,1,2-Trichloroethane (TCE)",Supporting & Related Material,"Letter, Memorandum, Email",2004-03-26T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f93 EPA-HQ-OPPT-2002-0056-0090,EPA,EPA-HQ-OPPT-2002-0056,"Letter to USEPA from Peter E. Voytek, Ph.D., Manager, Patton Boggs LLP, re: Testing Consent Order for 1,1,2-Trichloroethane",Supporting & Related Material,"Letter, Memorandum, Email",2004-03-05T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f81 EPA-HQ-OPPT-2002-0056-0089,EPA,EPA-HQ-OPPT-2002-0056,"Email from John Schaeffer, U.S. Environmental Protection Agency (USEPA) to Peter Voytek, Hazardous Air Pollutants (HAP) Task Force re the use of emulphor in toxicity studies.",Supporting & Related Material,"Letter, Memorandum, Email",2004-03-03T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f65 EPA-HQ-OPPT-2002-0056-0087,EPA,EPA-HQ-OPPT-2002-0056,"Notes from telephone conversation between John Schaeffer, U.S. Environmental Protection Agency (USEPA) and Peter Voytek, Hazardous Air Pollutants (HAP) Task Force.",Supporting & Related Material,Meeting or Teleconference Materials,2004-03-03T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f32 EPA-HQ-OPPT-2002-0056-0088,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Peter Voytek, Hazardous Air Pollutants (HAP) Task Force, from Greg Schweer, Chief, Chemical Information and Testing Branch, U.S. Environmental Protection Agency (USEPA) re Dose Level Selection for 1,1,2-Trichloroethane (TCE) in Tier II Testing",Supporting & Related Material,"Letter, Memorandum, Email",2004-03-03T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f4d EPA-HQ-OPPT-2002-0056-0085,EPA,EPA-HQ-OPPT-2002-0056,Use of PBPK Modeling in Dose Selection,Supporting & Related Material,Report,2004-03-03T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5efb EPA-HQ-OPPT-2002-0056-0086,EPA,EPA-HQ-OPPT-2002-0056,"Email from Rob Dewoskin, National Center for Environmental Assessment USEPA/NCEA to John Schaeffer, U.S. Environmental Protection Agency (USEPA).",Supporting & Related Material,"Letter, Memorandum, Email",2004-03-03T05:00:00Z,2004,3,,,2006-10-23T16:41:09Z,,0,0,09000064800b5f18 EPA-HQ-OPPT-2002-0056-0084,EPA,EPA-HQ-OPPT-2002-0056,"Route-to-Route Extrapolation of 1,1,2-Trichloroethane Studies from the Oral Route to Inhalation Using Physiologically Based Pharmacokinetic Models: Carcinogenicity",Supporting & Related Material,Report,2004-01-23T05:00:00Z,2004,1,,,2006-10-23T16:41:09Z,,0,0,09000064800b5ee6 EPA-HQ-OPPT-2002-0056-0083,EPA,EPA-HQ-OPPT-2002-0056,"Letter to OPPT Document Control Office, USEPA from Peter Voytek, HAP Task Force Manager, transmitting the ""Final Report required under the Enforceable Consent Agreement [ECA] for 1,1,2-Trichloroethane""",Supporting & Related Material,"Letter, Memorandum, Email",2004-01-23T05:00:00Z,2004,1,,,2006-10-23T16:41:09Z,,0,0,09000064800b5ed7 EPA-HQ-OPPT-2002-0056-0082,EPA,EPA-HQ-OPPT-2002-0056,"Letter to Document Control Office and to Richard W. Leukroth USEPA, from Peter E. Voytek, Manager of HAP Task Force, focusing on ""Testing Consent Order for 1,1,2-Trichloroethane; Interim Report"".",Supporting & Related Material,"Letter, Memorandum, Email",2003-12-24T05:00:00Z,2003,12,,,2006-10-23T16:41:09Z,,0,0,09000064800b5ec1 EPA-HQ-OPPT-2002-0056-0080,EPA,EPA-HQ-OPPT-2002-0056,"Amended Report: Pharmacokinetices of 1,1,2-Trichloroethane in Rats and Mice, with Cover Letter from Harvey Bolton, Pacific Northwest National Laboratory, to Peter Voytek, HAP Task Force",Supporting & Related Material,Report,2003-08-28T04:00:00Z,2003,8,,,2006-10-23T16:41:09Z,,0,0,09000064800b5e89 EPA-HQ-OPPT-2002-0056-0079,EPA,EPA-HQ-OPPT-2002-0056,"A letter to EPA OPPT from Peter Voytek, HAP Task Force, regarding Tier 1 Modified Reports for 1,1,2-Trichloroethane submitted by Pacific Northwest National Laboratories and The Sapphire Group (See OPPT-2002-0056-0080 and OPPT-2002-0056-0081)",Supporting & Related Material,"Letter, Memorandum, Email",2003-08-28T04:00:00Z,2003,8,,,2006-10-23T16:41:09Z,,0,0,09000064800b5e70 EPA-HQ-OPPT-2002-0056-0081,EPA,EPA-HQ-OPPT-2002-0056,"Physiologically Based Pharmacokinetic Model Development, Simulations and Sensitivity Analysis for Repeated Exposure to 1,1,2-Trichloroethane (TCE) [Revised] with Cover Letter from Michael Gargas, The Sapphire Group, to Peter Voytek, HAP Task Force",Supporting & Related Material,Report,2003-08-28T04:00:00Z,2003,8,,,2006-10-23T16:41:09Z,,0,0,09000064800b5ea8 EPA-HQ-OPPT-2002-0056-0072,EPA,EPA-HQ-OPPT-2002-0056,"[Signed] Addendum Modification to Enforceable Consent Agreement for 1,1,2-Trichloroethane (TCE) CAS No. 79-00-5",Supporting & Related Material,Report,2003-07-16T04:00:00Z,2003,7,,,2006-10-23T16:41:08Z,,0,0,09000064800b5dc6 EPA-HQ-OPPT-2002-0056-0058,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane (TCE); EPA Program Review: Notice of Availability",Notice,Federal Register Document,2003-07-09T04:00:00Z,2003,7,,,2008-01-08T21:14:37Z,40944,0,0,09000064800b5c69 EPA-HQ-OPPT-2002-0056-0068,EPA,EPA-HQ-OPPT-2002-0056,"Letter from P Oshida, EPA, to P Voytek, HAP Task Force, regarding Completion of the EPA Program Review for 1,1,2-Trichloroethane (TCE) and Modification to the TCE Enforceable Consent Agreement (ECA)",Supporting & Related Material,"Letter, Memorandum, Email",2003-07-02T04:00:00Z,2003,7,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d55 EPA-HQ-OPPT-2002-0056-0071,EPA,EPA-HQ-OPPT-2002-0056,"Addendum Modification to Enforceable Consent Agreement for 1,1,2-Trichloroethane (TCE) CAS No. 79-00-5",Supporting & Related Material,Report,2003-07-02T04:00:00Z,2003,7,,,2006-10-23T16:41:08Z,,0,0,09000064800b5da4 EPA-HQ-OPPT-2002-0056-0069,EPA,EPA-HQ-OPPT-2002-0056,"Program Review Report on the Enforceable Consent Agreement for 1,1,2-Trichloroethane (Cas No. 79-00-5)",Supporting & Related Material,Report,2003-07-02T04:00:00Z,2003,7,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d6c EPA-HQ-OPPT-2002-0056-0070,EPA,EPA-HQ-OPPT-2002-0056,Modifications to Tier II Testing and Reporting Activities [Enclosure 2 to OPPT-2002-0056-0068],Supporting & Related Material,Report,2003-07-02T04:00:00Z,2003,7,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d88 EPA-HQ-OPPT-2002-0056-0064,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA, to the HAP Task Force, with Attached Technical Consultation Meeting on 1,1,2-Trichloroethane (TCE) -- EPA Tier 1 Program Review Update",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-24T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5cfa EPA-HQ-OPPT-2002-0056-0067,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA, to the HAP Task Force, with a Revised Table 1 and EPA Modifications",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-24T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d38 EPA-HQ-OPPT-2002-0056-0065,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA, to the HAP Task Force, with Attached Table 1--Required Testing, Test Standards, and Reporting Requirements for TCE - Modifications/Revisions (??) to Tier II Testing and Reporting Activities",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-24T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d0b EPA-HQ-OPPT-2002-0056-0066,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA, with Attached HAP Task Force Response to the Revised Table 1 Footnotes",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-24T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5d27 EPA-HQ-OPPT-2002-0056-0062,EPA,EPA-HQ-OPPT-2002-0056,Modeling Blood/Plasma Concentrations in Dosed Feed and Dosed Drinking Water Toxicology Studies,Supporting & Related Material,Publication,2003-06-23T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5cd0 EPA-HQ-OPPT-2002-0056-0061,EPA,EPA-HQ-OPPT-2002-0056,"Expression, Catalytic Activity, and Inducibility of Cytochrome P450 2E1 (CYP2E1) in the Rat Central Nervous System",Supporting & Related Material,Publication,2003-06-23T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5cc2 EPA-HQ-OPPT-2002-0056-0060,EPA,EPA-HQ-OPPT-2002-0056,Light-Dark Cycle Modulates Drinking to Homeostatic Challenges,Supporting & Related Material,Publication,2003-06-23T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5c9c EPA-HQ-OPPT-2002-0056-0063,EPA,EPA-HQ-OPPT-2002-0056,"Meeting Summary -- Technical Consultation Meeting on the TCE ECA, March 12, 2003 -- 4:30PM - 6:30PM",Supporting & Related Material,Meeting or Teleconference Materials,2003-06-23T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5ce6 EPA-HQ-OPPT-2002-0056-0059,EPA,EPA-HQ-OPPT-2002-0056,"Program Review Report on the Enforceable Consent Agreement for 1,1,2-Trichloroethane -- CAS No. 79-00-5",Supporting & Related Material,Report,2003-06-23T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5c83 EPA-HQ-OPPT-2002-0056-0057,EPA,EPA-HQ-OPPT-2002-0056,"Letter from M. Owens, Borden Chemicals & Plastics (BCP), to P. Voytek, HAP Task Force, regarding HAP Task Force Assessment",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-09T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5c4c EPA-HQ-OPPT-2002-0056-0056,EPA,EPA-HQ-OPPT-2002-0056,"Letter from C. Norman, Patton Boggs LLP, to P. Oshida, EPA OPPTS, confirming P. Voytek's Request to Remove Borden Chemicals and Plastics from the HAP Task Force Assessment Requirements.",Supporting & Related Material,"Letter, Memorandum, Email",2003-06-09T04:00:00Z,2003,6,,,2006-10-23T16:41:08Z,,0,0,09000064800b5c31 EPA-HQ-OPPT-2002-0056-0055,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Philip Oshida, EPA OPPT, to Peter Voytek, HAP Task Force, re: Tier 1 Pharmacokinetics Report",Supporting & Related Material,"Letter, Memorandum, Email",2003-05-27T04:00:00Z,2003,5,,,2006-10-23T16:41:08Z,,0,0,09000064800b5c18 EPA-HQ-OPPT-2002-0056-0001,EPA,EPA-HQ-OPPT-2002-0056,"1,1,2-Trichloroethane, Tier 1 Program Review Testing; Notice of Availability and Solicitation of Comments",Notice,Federal Register Document,2002-10-16T04:00:00Z,2002,10,2002-10-16T04:00:00Z,2002-11-16T04:59:59Z,2008-01-08T21:22:52Z,63913,0,0,09000064800b577b EPA-HQ-OPPT-2002-0056-0053,EPA,EPA-HQ-OPPT-2002-0056,"Letter from John Schaeffer, EPA OPPT CITB CCD, with Addendum Modification to Enforceable Consent Agreement for 1,1,2-Trichloroethane (1,1,2-TCE) CAS No. 79-00-5",Supporting & Related Material,"Letter, Memorandum, Email",2002-10-04T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5be3 EPA-HQ-OPPT-2002-0056-0052,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Charles Auer, EPA OPPT, to Peter Voytek, HAP Task Force, regarding Modifications to the Enforceable Consent Agreement for 1,1,2Trichloroethane, with Attached Modification Addendum",Supporting & Related Material,"Letter, Memorandum, Email",2002-10-02T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5bca EPA-HQ-OPPT-2002-0056-0047,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Peter Voytek, HAP Task Force, to Rich Leukroth and John Schaeffer, EPA OPPT, regarding the Fourth Interim Status Report: Schedule for Toxicity Testing & PBPK Modeling Activities for 1,1,2-Trichloroethane Interim Reports - Year 2002",Supporting & Related Material,Report,2002-10-01T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b58 EPA-HQ-OPPT-2002-0056-0049,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA OPPT, to Peter Voytek, HAP Task Force, regarding 1,1,2-Trichloroethane Technical Consultation Meeting in RTP, NC",Supporting & Related Material,Other,2002-10-01T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b87 EPA-HQ-OPPT-2002-0056-0051,EPA,EPA-HQ-OPPT-2002-0056,"Meeting Sumary of 8/13/2002 Technical Consultation Meeting on the 1,1,2-Trichloroethane Enforceable Consent Agreement with Agenda and Overheads of Presentations from Peter Voytek, HAP Task Force, and Michael Gargas, The Sapphire Group",Supporting & Related Material,Meeting or Teleconference Materials,2002-10-01T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5bb2 EPA-HQ-OPPT-2002-0056-0048,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA OPPT, to Michel Stevens, EPA ORD, regarding the HAP Task Force Request for a Technical Consultation Meeting",Supporting & Related Material,Other,2002-10-01T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b6f EPA-HQ-OPPT-2002-0056-0050,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA OPPT, to Michel Stevens, EPA ORD, regarding the Technical Consultation Meeting for 1,1,2-Trichloroethane, held on August 13, 2002",Supporting & Related Material,Other,2002-10-01T04:00:00Z,2002,10,,,2006-10-23T16:41:08Z,,0,0,09000064800b5ba0 EPA-HQ-OPPT-2002-0056-0046,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Charles Auer, EPA OPPT, to Peter Voytek, HAP Task Force, with one attachment: Preliminary EPA Technical Analysis of Proposed Industry Pharmacokinetics (PK) Strategy for 1,1,2-Trichloroethane",Supporting & Related Material,Other,2002-09-30T04:00:00Z,2002,9,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b3c EPA-HQ-OPPT-2002-0056-0045,EPA,EPA-HQ-OPPT-2002-0056,"Proposal for Pharmacokinetics Study of 1,1,2-Trichloroethane, with Cover Letter from Peter Voytek, HAP Task Force, to EPA",Supporting & Related Material,Study,2002-09-27T04:00:00Z,2002,9,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b20 EPA-HQ-OPPT-2002-0056-0044,EPA,EPA-HQ-OPPT-2002-0056,"Letter, from Peter Voytek, HAP Task Force, to EPA, regarding the Testing Consent Order for 1,1,2-Trichloroethane, with one attachment: Schedule for Toxicity Testing and PBPK Modeling Activities for 1,1,2-Trichloroethane Interim Reports - Year 2000",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-27T04:00:00Z,2002,9,,,2006-10-23T16:41:08Z,,0,0,09000064800b5b01 EPA-HQ-OPPT-2002-0056-0043,EPA,EPA-HQ-OPPT-2002-0056,"Physiologically Based Pharmacokinetic Model Development, Simulations, and Sensitivity Analysis for Repeated Exposure to 1,1,2-Trichloroethane, with Cover Transmittal Letters from The Sapphire Group to the HAP Task Force & from HAP Task Force to EPA",Supporting & Related Material,Study,2002-09-24T04:00:00Z,2002,9,,,2006-10-23T16:41:08Z,,0,0,09000064800b5ae9 EPA-HQ-OPPT-2002-0056-0019,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Peter Voytek, HAP Task Force Manager, to EPA, regarding Request for Modification of 90-Day Inhalation Toxicity Study",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b58f2 EPA-HQ-OPPT-2002-0056-0013,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Charles Auer, EPA OPPT, to Peter Voytek, HAP Task Manager, regarding PK ECA for 1,1,2-Trichloroethane (OPPTS-42198C)",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5876 EPA-HQ-OPPT-2002-0056-0039,EPA,EPA-HQ-OPPT-2002-0056,"Final Report: Acute Inhalation Toxicity (with Histopathology) -- Study of 1,1,2-Trichloroethane (1,1,2-TCE) in Rats",Supporting & Related Material,Report,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5a6f EPA-HQ-OPPT-2002-0056-0041,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Douglas Terry, Dow USA Texas Operations, to Peter Voytek, HAP Task Force Manager, regarding Analysis of 1,1,2-Trichloroethane Samples [with data attached]",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:08Z,,0,0,09000064800b5aab EPA-HQ-OPPT-2002-0056-0007,EPA,EPA-HQ-OPPT-2002-0056,Appendix C: PK/Mech Procedures and Route-to-Route Extrapolation Reporting,Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:06Z,,0,0,09000064800b5802 EPA-HQ-OPPT-2002-0056-0010,EPA,EPA-HQ-OPPT-2002-0056,"Appendix E.1: Existing in Vivo Cytogenetics Studies - B. 1,1,2-Trichloroethane: Evidence of Genotoxicity from Short-Term Tests (Mazzullo M., et al, 1986)",Supporting & Related Material,Publication,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5841 EPA-HQ-OPPT-2002-0056-0029,EPA,EPA-HQ-OPPT-2002-0056,"EPA General Contact Report: Follow-up on Technical Consultation on the May 21st Teleconference between EPA and the HAP Task Force",Supporting & Related Material,Meeting or Teleconference Materials,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b59b1 EPA-HQ-OPPT-2002-0056-0040,EPA,EPA-HQ-OPPT-2002-0056,"Chemical Dosimetry Group Final Report: Pharmacokinetics of 1,1,2-Trichloroethane in Rats and Mice",Supporting & Related Material,Study,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5a8f EPA-HQ-OPPT-2002-0056-0015,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Peter Voytek, HAP Task Force, to the DCO, EPA, re Interim Status Report on Testing Conducted Pursuant to 1,1,2-TCE Consent Order - Schedule for Toxicity Testing & PBPK Modeling Activities for 1,1,2-TCE Interim Reports - Year 2002",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b589c EPA-HQ-OPPT-2002-0056-0018,EPA,EPA-HQ-OPPT-2002-0056,"Subchronic Inhalation Testing of 1,1,2-Trichloroethane Study Plan with Cover Letter",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b58dd EPA-HQ-OPPT-2002-0056-0034,EPA,EPA-HQ-OPPT-2002-0056,"Letter from John Schaeffer, EPA OPPT, with Addendum Modification to Enforceable Consent Agreement for 1,1,2-Trichloroethane (1,1,2-TCE) CAS No. 79-00-5",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5a0a EPA-HQ-OPPT-2002-0056-0036,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Charles Auer, EPA OPPT, to Peter Voytek, HAP Task Force, regarding its Request for Modifications to the Enforceable Consent Agreement for 1,1,2-Trichloroethane, with attached Modifications to the ECA",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5a32 EPA-HQ-OPPT-2002-0056-0027,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Peter Voytek, HAP Task Force, to Richard Leukroth, EPA OPPT, regarding Subchronic Dosing",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b598d EPA-HQ-OPPT-2002-0056-0012,EPA,EPA-HQ-OPPT-2002-0056,"Appendix E: Existing Toxicity Studies - E.3 Existing Oncogenicity Study - Bioassay of 1,1,2-Trichloroethane for Possible Carcinogenicity (NCI, 1978)",Supporting & Related Material,Report,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b585f EPA-HQ-OPPT-2002-0056-0004,EPA,EPA-HQ-OPPT-2002-0056,"Enforceable Consent Agreement for 1,1,2-Trichloroethane (CAS No. 79-00-5)",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:06Z,,0,0,09000064800b57bf EPA-HQ-OPPT-2002-0056-0038,EPA,EPA-HQ-OPPT-2002-0056,"Letter from Nori Nichols-Schrek, Batelle, to Caffy Norman, Patton Boggs, regarding Service agreement with the HAP Task Force with signed Agreement between Batelle and the HAP Task Force and Pharmacokinetics Study Protocol attached",Supporting & Related Material,"Letter, Memorandum, Email",2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5a57 EPA-HQ-OPPT-2002-0056-0006,EPA,EPA-HQ-OPPT-2002-0056,"Appendix B: TSCA Toxicity Testing Guidelines for 1,1,2-Trichloroethane",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:06Z,,0,0,09000064800b57e6 EPA-HQ-OPPT-2002-0056-0009,EPA,EPA-HQ-OPPT-2002-0056,"Appendix E.1: Existing in Vivo Cytogenetics Studies -- A. An Investigation into the Activation and Deactivation of Chlorinated Hydrocarbons to Genotoxins in Metabolically Competent Human Cells (Doherty Ann T. et al, 1996)",Supporting & Related Material,Publication,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b5832 EPA-HQ-OPPT-2002-0056-0026,EPA,EPA-HQ-OPPT-2002-0056,"EPA General Contact Report of Telephone Conference Call between Peter Voytek, HAP Task Force, and Richard Leukroth and Michael Stevens, EPA, regarding Testing being Conducted under an Enforceable Consent Agreement for 1,1,2-Trichloroethane",Supporting & Related Material,Meeting or Teleconference Materials,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b597f EPA-HQ-OPPT-2002-0056-0030,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Rich Leukroth, EPA OPPT, to Peter Voytek, HAP Task Force, Requesting Comments on Modifications to the Enforceable Consent Agreement for 1,1,2-Trichloroethane",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b59bd EPA-HQ-OPPT-2002-0056-0031,EPA,EPA-HQ-OPPT-2002-0056,"E-mail from Peter Voytek, HAP Task Force, to Rich Leukroth, EPA OPPT, regarding 6/01/2001 E-mail from Rich Leukroth (see OPPT-2002-0056-0030) Requesting Comments on Modifications to the Enforceable Consent Agreement for 1,1,2-Trichloroethane",Supporting & Related Material,Other,2002-09-17T04:00:00Z,2002,9,,,2006-10-23T16:41:07Z,,0,0,09000064800b59d5