id,agency_id,docket_id,title,document_type,subtype,posted_date,posted_year,posted_month,comment_start_date,comment_end_date,last_modified,fr_doc_num,open_for_comment,withdrawn,object_id EPA-HQ-OPP-2021-0641-0310,EPA,EPA-HQ-OPP-2021-0641,"Response to Public Comments on EPA’s Registration of the New Active Ingredient, Isocycloseram",Supporting & Related Material,Comment Response,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:40Z,,0,0,09000064b908a22e EPA-HQ-OPP-2021-0641-0311,EPA,EPA-HQ-OPP-2021-0641,"Final Environmental Fate and Ecological Risk Assessment (ERA) and Biological Evaluation (BE) with Associated Effects Determinations for Federally Listed Endangered and Threatened Species and Designated Critical Habitat for the Section 3 Registration of the New Active Ingredient Isocycloseram",Supporting & Related Material,Risk Assessment,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:42Z,,0,0,09000064b908a22f EPA-HQ-OPP-2021-0641-0307,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram. Petition for the Establishment of Permanent Tolerances and Registration for New Use on Tree Nuts (Crop Group 14-12). Addendum to the Summary of Analytical Chemistry Residue Data and Dietary Exposure Assessment,Supporting & Related Material,Petition,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:32Z,,0,0,09000064b908946e EPA-HQ-OPP-2021-0641-0309,EPA,EPA-HQ-OPP-2021-0641,Memorandum Supporting Final Decision to Approve Registration for the New Active Ingredient of Isocycloseram,Supporting & Related Material,Decision,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:37Z,,0,0,09000064b908a22d EPA-HQ-OPP-2021-0641-0308,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram. Addendum to the Occupational and Residential Exposure Assessment for the New Active Ingredient Isocycloseram for Updated Commercial Seed Treatment Uses,Supporting & Related Material,Risk Assessment,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:35Z,,0,0,09000064b908946f EPA-HQ-OPP-2021-0641-0305,EPA,EPA-HQ-OPP-2021-0641,"Pesticide Tolerance; Exemptions, Petitions, Revocations, etc.: Isocycloseram",Rule,,2025-11-20T05:00:00Z,2025,11,2025-11-20T05:00:00Z,2026-01-21T04:59:59Z,2026-01-24T13:16:37Z,2025-20460,0,0,09000064b908a60d EPA-HQ-OPP-2021-0641-0313,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram EFED Appendix P. Species Effects Determinations and Predictions of Jeopardy,Supporting & Related Material,Data,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:47Z,,0,0,09000064b908a231 EPA-HQ-OPP-2021-0641-0306,EPA,EPA-HQ-OPP-2021-0641,Endangered Species Act Section 7(d) Consistency Determination with Respect to the Application for the Registration of Products Containing the New Active Ingredient Isocycloseram,Supporting & Related Material,Memorandum,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:30Z,,0,0,09000064b908946d EPA-HQ-OPP-2021-0641-0312,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram. Addendum to the Human Health Risk Assessment for the Section 3 Registration of the New Active Ingredient Isocycloseram on Treated Seeds, Agricultural Field Crops, Indoor/Outdoor Residential Areas, Residential/Commercial Turf, Greenhouse, Commercial/Industrial Areas, Industrial Structures, and Agricultural Structures",Supporting & Related Material,Risk Assessment,2025-11-20T05:00:00Z,2025,11,,,2025-11-21T00:36:45Z,,0,0,09000064b908a230 EPA-HQ-OPP-2021-0641-0008,EPA,EPA-HQ-OPP-2021-0641,"Review of Submitted Data Relating to Claims of Greater-than-Additive (GTA) Mixture Toxicity Associated with the Proposed New Active Ingredient, Isocycloseram (PC Code 129220)",Supporting & Related Material,Data,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0c03e EPA-HQ-OPP-2021-0641-0025,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram A21550 400SC Insecticide - Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d1ad58 EPA-HQ-OPP-2021-0641-0007,EPA,EPA-HQ-OPP-2021-0641,Memorandum Supporting Proposed Decision to Approve Registration for the New Active Ingredient of Isocycloseram,Supporting & Related Material,Decision,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0c03d EPA-HQ-OPP-2021-0641-0012,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram. Chronic Aggregate Dietary (Food and Drinking Water) Exposure and Risk Assessment for the Section 3 Registration Action,Supporting & Related Material,Risk Assessment,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0efeb EPA-HQ-OPP-2021-0641-0009,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram: Summaiy of Hazai·d and Science Policy Council (HASPOC) Meeting on October 27, 2022: Recommendations on the Need for a Subchronic Inhalation Toxicity Study, an Immunotoxicity Study and a Developmental Neurotoxicity Study, and Adequacy of Subchronic Neurotoxicity, Rat and Rabbit Developmental Toxicity, and Two-Generation Reproduction Toxicity Studies",Supporting & Related Material,Meeting Materials,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:10:36Z,,0,0,09000064b8d0efe8 EPA-HQ-OPP-2021-0641-0016,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram. Occupational and Residential Exposure Assessment for Proposed Uses of the New Active Ingredient Isocycloseram,Supporting & Related Material,Risk Assessment,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:10:36Z,,0,0,09000064b8d0efef EPA-HQ-OPP-2021-0641-0021,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram: Draft Environmental Fate and Ecological Risk Assessment (ERA) for the Proposed FIFRA Section 3 Registration and Biological Evaluation (BE) with Associated Effects Determinations for Federally Listed Endangered and Threatened Species and Designated Critical Habitat,Supporting & Related Material,Risk Assessment,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:10:20Z,,0,0,09000064b8d1ab25 EPA-HQ-OPP-2021-0641-0018,EPA,EPA-HQ-OPP-2021-0641,Appendix P. Isocycloseram Species Effects Determinations and Predictions of Likely Jeopardy-5-1-25,Supporting & Related Material,Fact/Data Sheet,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:08Z,,0,0,09000064b8d1a311 EPA-HQ-OPP-2021-0641-0026,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram A21708 CP For control of mites, thrips, true bugs, lepidopterous pests, and other insects in Brassica Head and Stem Vegetables, Crop Group 5-16; Brassica Leafy Greens, Crop Subgroup 4-16B - Master Label",Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d1ad59 EPA-HQ-OPP-2021-0641-0020,EPA,EPA-HQ-OPP-2021-0641,Appendix T Isocycloseram CoA Range 05-08-25,Supporting & Related Material,Fact/Data Sheet,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:16:18Z,,0,0,09000064b8d1a314 EPA-HQ-OPP-2021-0641-0029,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram A22128 Cockroach Gel Bait - Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:29:58Z,,0,0,09000064b8d2008c EPA-HQ-OPP-2021-0641-0011,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram. Report of the Residues of Concern Knowledgebase Subcommittee (ROCKS),Supporting & Related Material,Report,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0efea EPA-HQ-OPP-2021-0641-0027,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram Alternate Brand Name: Equento 400FS A22725 ST - Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:29:58Z,,0,0,09000064b8d1ad5a EPA-HQ-OPP-2021-0641-0010,EPA,EPA-HQ-OPP-2021-0641,"Benefits for Proposed Agricultural Foliar, Soil-directed, and Seed Treatment Uses of Isocycloseram (PC# 129220) on Certain Row Crops, Foliar Uses on Certain Specialty Crops, and in Non-Agricultural Uses (DP# 465648, 466752)",Supporting & Related Material,Memorandum,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:10:36Z,,0,0,09000064b8d0efe9 EPA-HQ-OPP-2021-0641-0028,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram Alternate Brand Name: Equento 100FS A22241 ST,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d2008b EPA-HQ-OPP-2021-0641-0013,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram. Petition for the Establishment of Permanent Tolerances and Registration for New Use on Brassica Head and Stem Vegetable (Crop Group 5-16), Bulb Vegetable (Crop Group 3-07), Barley, Citrus Fruit (Crop Group 10-10), Corn (Field, Pop, Seed), Cottonseed",Supporting & Related Material,Petition,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0efec EPA-HQ-OPP-2021-0641-0015,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram. Human Health Risk Assessment for the Section 3 Registration of the New Active Ingredient Isocycloseram on Treated Seeds, Agricultural Field Crops, Indoor/Outdoor Residential Areas, Residential/Commercial Turf, Greenhouse, Commercial/Industrial Areas, Industrial Structures, and Agricultural Structures",Supporting & Related Material,Risk Assessment,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0efee EPA-HQ-OPP-2021-0641-0031,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram Atexzo Alternate Brand Name: Vykenda - Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:29:57Z,,0,0,09000064b8d2008e EPA-HQ-OPP-2021-0641-0014,EPA,EPA-HQ-OPP-2021-0641,Rebuttal to Agency’s Decision to Revoke Reduced Risk Determination for Isocycloseram on Cotton and Soybeans,Supporting & Related Material,Decision,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d0efed EPA-HQ-OPP-2021-0641-0017,EPA,EPA-HQ-OPP-2021-0641,Drinking Water Exposure Assessment for the New Active Ingredient Isocycloseram,Supporting & Related Material,Risk Assessment,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:28:38Z,,0,0,09000064b8d1a310 EPA-HQ-OPP-2021-0641-0022,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram Technical Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d1ad55 EPA-HQ-OPP-2021-0641-0024,EPA,EPA-HQ-OPP-2021-0641,"Isocycloseram Not for Sale, Sale Into, Distribution and/or Use in Nassau and Suffolk Counties of New York State A21550 CP - Master Label",Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d1ad57 EPA-HQ-OPP-2021-0641-0006,EPA,EPA-HQ-OPP-2021-0641,Public Participation for Isocycloseram,Other,Public Participation,2025-05-09T04:00:00Z,2025,5,2025-05-09T04:00:00Z,2025-06-11T03:59:59Z,2025-06-12T09:00:18Z,,0,0,09000064b8d0efe7 EPA-HQ-OPP-2021-0641-0023,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram A22466 CP Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d1ad56 EPA-HQ-OPP-2021-0641-0030,EPA,EPA-HQ-OPP-2021-0641,Isocycloseram A21377 CP Alternate Brand Name: Incipio - Master Label,Supporting & Related Material,,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:02:05Z,,0,0,09000064b8d2008d EPA-HQ-OPP-2021-0641-0019,EPA,EPA-HQ-OPP-2021-0641,Appendix T Isocycloseram Coach 05-08-25,Supporting & Related Material,Fact/Data Sheet,2025-05-09T04:00:00Z,2025,5,,,2025-05-21T19:16:18Z,,0,0,09000064b8d1a313 EPA-HQ-OPP-2021-0641-0003,EPA,EPA-HQ-OPP-2021-0641,"Pesticide Product Registration: Applications for New Active Ingredients, February 2022",Notice,,2022-03-23T04:00:00Z,2022,3,2022-03-23T04:00:00Z,2022-04-23T03:59:59Z,2022-04-22T01:00:46Z,2022-06163,0,0,0900006484fdc82e EPA-HQ-OPP-2021-0641-0001,EPA,EPA-HQ-OPP-2021-0641,Pesticide Petitions Filed for Residues of Pesticide Chemicals in or on Various Commodities,Proposed Rule,,2022-03-22T04:00:00Z,2022,3,2022-03-22T04:00:00Z,2022-04-22T03:59:59Z,2022-03-27T01:00:46Z,2022-06046,0,0,0900006484fd8ae5 EPA-HQ-OPP-2021-0641-0002,EPA,EPA-HQ-OPP-2021-0641,"Syngenta Crop Protection, LLC Notice of Filing Pesticide Petition to establish a tolerance for residues of [Isocycloseram] in or on the raw agricultural commodity [Almond, Halls] et al.",Supporting & Related Material,Petition,2022-03-22T04:00:00Z,2022,3,,,2022-03-23T02:08:34Z,,0,0,0900006484f6e9fb